Glycated alpha-synuclein and it emerging role in early onset of Parkinson’s disease
Objective: To elucidate, the molecular mechanism underlying glycated α-Syn mediated dopaminergic (DAergic) neurodegeneration in the substantia nigra (SN) via the AGE/RAGE signaling pathway. Background: Intracytoplasmic…Changes in word fluency tasks and cognitive function before and after the COVID-19 epidemic in patients with Parkinson’s disease:PD.
Objective: The purpose of this study is to investigate the changes in cognitive function and frontal lobe function in PD before and after self-restraint due…Can very early levodopa prevent self-injury in Lesch-Nyhan Disease?
Objective: To determine whether levodopa treatment starting at a very young age can prevent the development of the full clinical phenotype in Lesch-Nyhan disease. Background:…Beyond Parkinson´s disease and synucleinopathies: unexpected identification of prodromal corticobasal syndrome by the updated MDS research criteria for prodromal PD
Objective: The aim of the current study was to determine the proportion of patients, initially classified as having prodromal Parkinson’s disease (pPD), phenoconverted to manifest…Apolipoprotein E e4 genotype affects early motor progression in Parkinson’s disease through an effect on cognition
Objective: To evaluate the relationship between APOE e4 genotype, cognition, and motor progression in early Parkinson’s disease (PD). Background: The Apolipoprotein E (APOE) e4 genotype…Sex-specific speech correlates of dysphagia in Parkinson’s disease
Objective: To identify speech characteristics that directly correlate with dysphagia in advanced Parkinson's disease (PD) patients, using both acoustic and perceptual analyses of speech, with…Effects of physical exercise interventions on cognitive function in Parkinson’s disease: an updated systematic review and meta-analysis of randomized controlled trials
Objective: To determine whether physical exercise interventions can improve cognitive function, including overall performance and specific domains, in patients with Parkinson’s disease (PD) and to…Prognostic significance of peripheral neutrophils and lymphocytes in early Parkinson’s disease
Objective: To explore whether peripheral blood neutrophils and lymphocytes are associated with longitudinal motor and cognitive decline in patients with early Parkinson’s disease (PD) and,…Myocardial sympathetic denervation biomarkers for early detection of prodromal DLB
Objective: Because of the time course of detecting DLB symptoms and signs, DLB is poorly diagnosed and hardly differentiate from AD, especially in early stage…Parkinson’s disease (PD) progression is associated with past exposure to organic contaminants in water at Marine Corps Base Camp Lejeune
Objective: To test whether PD progression is more rapid in individuals who were exposed to volatile organic compounds in the water supply at Camp Lejeune…
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