Teleprogramming Reduces the Time Needed to Optimize DBS Therapy: Results from the ROAM-DBS study
Objective: To present early outcomes from the ROAM-DBS (Deep Brain Stimulation) trial on the clinical efficacy of teleprogramming for DBS demonstrating more rapid improvement when…A multimodal approach for diagnosis of early Multiple System Atrophy (MSA)
Objective: To describe the use of neuroimaging and fluid biomarkers to improve the diagnostic accuracy of early MSA. Background: The diagnosis of early MSA is…Are GDNF receptors the gatekeepers of GDNF efficacy during progressive nigrostriatal neuron loss?
Objective: To determine if GDNF receptor expression levels in the striatum or substantia nigra (SN) change in relation to differences in tyrosine hydroxylase (TH) and…Long-term evolution of advanced Parkinson’s disease burden: second interim results from the international PROSPECT observational study
Objective: To evaluate the long-term evolution of clinical and economic outcomes and treatment patterns of patients with advanced Parkinson’s disease (PD) who have symptoms that…Sport based approach in patients with Parkinson’s disease
Objective: We describe our 2-year experience implementing a sport based approach in patients with Parkinson’s Disease (PD). Background: PD is a progressive neurological disorder. The…Identification of atlastin genetic modifiers in a Hereditary Spastic Paraplegia model in Drosophila
Objective: To identify genetic modifiers of decreased locomotion and neuromuscular junction defects associated with atlastin knockdown in motor neurons. Background: Hereditary spastic paraplegias (HSPs) are…Pediatric Myoclonus-Dystonia misdiagnosed as CASPR2 encephalitis – a diagnostic challenge
Objective: Describe the clinical/laboratory challenges in diagnosis of myoclonus-dystonia at a young age Background: SGCE Myoclonus-Dystonia (SGCE-M-D) is a genetic movement disorder characterized by multifocal…Concordant RNA patterns in Parkinson’s disease brain and peripheral blood.
Objective: To investigate the molecular correlates of clinical heterogeneity in Parkinson’s disease (PD) in the striatum and peripheral blood. Background: The molecular basis for clinical…Melatonin for huntington disease (HD) gene carriers with HD-related sleep disturbance – a pilot study
Objective: To evaluate the efficacy of exogenous melatonin in improving sleep quality in Huntington disease (HD) gene carriers. Background: Various sleep disorders have been identified…Hypoxic brain injury: a rare cause of chorea and dystonia
Objective: To present a rare case of chorea and dystonia development in a young patient following cardiac arrest. Background: An hypoxic brain injury can potentially…
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