Investigate the association of MAPT haplotype and neuroanatomical structure and its influence on the risk of Parkinson’s disease
Objective: To investigate if the vulnerability of Parkinson’s Disease (PD) can be reflected in the neuroanatomical structure in different MAPT haplotype carriers. Background: It has…Needs and priorities of people with Parkinson’s and care partners regarding neuropsychiatric symptoms
Objective: To examine the experiences of people with Parkinson’s disease (PD) and care partners (CPs) regarding cognitive, mood, behavioral, and sleep issues. Background: Neuropsychiatric symptoms…Efficacy and safety of safinamide in PD patients over 70 years vs. under 70 years old;
Objective: To search for any differences between efficacy and safety of safinamide in PD patients over 70 years vs. under 70 years old. Background: Safinamide…The Prevalence of Primary Tauopathies in Ireland; a Clinically-Defined Study in the Province of Leinster: design and initial data.
Objective: To investigate the epidemiology and phenomenology of PSP and CBS within the province of Leinster. Background: PSP and CBS are uncommon parkinsonian disorders. Studies…Measures of trancranial magnetic evoked potentials for prediction of response to ventriculoparitoneal shunt In normal pressure hydrocephalus
Objective: Assess the utility of an EEG-TMS-based evaluation for prediction of response to ventriculoperitoneal shunt (VPS) in normal pressure hydrocephalus (NPH). Background: VPS is the…Bowel symptoms and management practices in Parkinson’s disease and related conditions: results from the PRIME-UK study.
Objective: To describe bowel symptoms and constipation management practices in a large, representative cross-sectional study of Parkinson’s and related disorders. Background: Bowel symptoms, particularly constipation,…Phenotypic presentation of essential tremor patients with Rapid eye movement disorder
Objective: To describe the prevalence of rapid eye movement disorder (RBD) among essential tremor (ET) patients and its correlates in terms of associated motor and…Neurofilament light chain, tau-PET and microglia-PET predict clinical progression in amyloid-negative corticobasal syndrome
Objective: A head-to-head comparison of neuroimaging (tau-PET, microglia-PET, structural MRI) and plasma biomarker Neurofilament light chain (NfL) as prognostic tools for longitudinal clinical trajectories in…Exome sequencing of 584 Chinese proband with brain calcification
Objective: The aim of this study is to evaluate the diagnostic value of whole exome sequencing in Chinese patients with brain calcification, and to provide exome sequencing-based insights into the genetic…Sex Is Not a Major Determinant of Pallidus Internus Deep Brain Stimulation Outcome in Dystonia
Objective: To investigate the role of sex as a biological variable in efficacy and safety of GPi DBS in adults with dystonia. Background: Sex- related…
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