Multimodal imaging analysis of autosomal recessive Parkinson’s disease.
Objective: To explore whether autosomal recessive forms of monogenic PD (mPD) might lead to cortical and white matter (WM) abnormalities in addition to dopaminergic denervation.…Early-onset levodopa-responsive Parkinsonism associated with dysarthria, pyramidalism, and dystonia: a rare condition that can benefit from a combined treatment approach.
Objective: To describe a rare case of early-onset parkinsonism (EOP) successfully treated with a combined therapeutic approach. Background: EOP is a rare condition manifesting with…Case of neuroferritinopathy with isolated dystonic leg cramps and normal neuroimaging
Objective: To describe a case of genetically proven neuroferritinopathy with isolated dystonic leg cramps and normal neuro-imaging. Background: Neuroferritinopathy(NF) is an autosomal dominant condition characterized…Subanesthetic infusion of ketamine produces long-term reduction in levodopa-induced dyskinesia and depression in individuals with Parkinson’s Disease
Objective: An open-label, dose-finding Phase I/II clinical trial was conducted to test safety and tolerability of low-dose ketamine infusion to treat levodopa-induced dyskinesia (LID), and…The effect of levodopa on the blood activity of calpains in patients with Parkinson’s disease
Objective: To evaluate the effect of levodopa on the blood activity of calpains in patients with PD Background: Parkinson's disease (PD) is a chronic progressive…Oculomotor changes in the premotor stage of LRRK2- G2019S associated Parkinson’s disease.
Objective: To analyse oculomotor differences among idiopathic PD patients (iPD), LRRK2-G2019S PD patients (LRRK2-G2019S PD), asymptomatic carriers of LRRK2-G2019S mutation (AsG2019S), and controls, evaluated by…Association between Parkinson’s Disease and Atrial Fibrillation: A Literature Review
Objective: Our literature review aims to summarize what has been reported in the literature with the next steps of looking at Kaiser Permanente (KP) to…Association of Increased Frontal White Matter A2A Receptor Availability with Decreased Frontal Gray Matter Volume in Patients with Parkinson’s Disease
Objective: We sought to investigate in vivo changes in A2A receptor availability in cerebral white matter of PD patients and its association with gray matter…Bradykinesia in Patients with Cervical Dystonia: Objective Assessment with Optical Sensor
Objective: To objectively quantify selected parameters of bradykinesia investigated by finger tapping in cervical dystonia patients using the Leap Motion Controller (LMC) sensor. Background: Bradykinesia,…PSP registry: preliminary cross-sectional results of the first 2 years of recruitment of a multicenter registry and biorepository.
Objective: To establish a multicenter PSP registry and biorepository in a province covering an area of 5,500,000 inhabitants, with 14 local and university hospitals. Background:…
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