Bradykinesia in Patients with Cervical Dystonia: Objective Assessment with Optical Sensor
Objective: To objectively quantify selected parameters of bradykinesia investigated by finger tapping in cervical dystonia patients using the Leap Motion Controller (LMC) sensor. Background: Bradykinesia,…3D Multi-Delay pCASL to Understand Perfusion Changes in Patients with Parkinson’s disease with Mild Cognitive Impairment
Objective: To understand perfusion changes in patients with Parkinson’s disease (PD) with well-characterized mild cognitive impairment (MCI) using 3D multi-delay pseudo-continuous Arterial Spin Labeling (pCASL)…Distinct characteristics of gut microbiome in patients with Parkinson’s disease according to the presence of premotor REM sleep behavior disorders
Objective: We aimed to investigate whether the composition and function of gut microbiome obtained from shotgun metagenomic sequencing are different between Parkinson’s disease (PD) patients…Increased MD and decreased FA reflect cognitive impairment in PSP
Objective: To identify white matter (WM) alterations associated with cognitive impairment in progressive supranuclear palsy (PSP). Background: PSP is accompanied with cognitive impairment [1;2], but…A newly implemented NGS-based method to detect GBA1 variants in patients with Parkinson’s disease
Objective: We aim to implement a new cost-effective and reliable next-generation-sequencing-based technology to test GBA1 gene in Parkinson disease (PD) patients. Background: Heterozygous variants in the…Integrated analysis of phase 3 trials of foslevodopa/foscarbidopa demonstrated that majority of reported infusion site AEs including infections were non serious, mild to moderate in severity and did not result in treatment discontinuation.
Objective: To characterize reported infusion site infection adverse events (AEs) and their clinical management in patients with Parkinson’s disease (PD) treated with foslevodopa/foscarbidopa (LDP/CDP). Background:…Tongue fasciculations and numbness: A case of calcifying pseudoneoplasm
Objective: To describe a 61-year-old female who presents with abnormal tongue movement found to have right frontoparietal calcifying pseudoneoplasm of the neuraxis (CAPNON). Background: CAPNON…Consideration of age and initial putaminal rim segment in distinguishing multiple system atrophy parkinsonian type
Objective: To improve diagnostic performance in distinguishing multiple system atrophy parkinsonian type (MSA-p), we investigated the iron deposition pattern in the putaminal lateral margin of…Is a Parkinson’s Sialorrhoea service effective?
Objective: Evaluate the efficacy and tolerance of Botulinum Toxin A (BoNT A) in managing sialorrhoea in People with Parkinsons (PwP)Assess impact on quality of life…Diagnostic challenges in a case of SLC6A3-related Dopamine Transporter Deficiency Syndrome
Objective: We report a case presenting with symptoms of classical Dopamine Transporter Deficiency Syndrome (DTDS) with negative results on initial whole-exome sequencing (WES), but eventually…
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