Subtyping Parkinson’s disease: Quality of life changes after subthalamic stimulation depend on nonmotor and motor symptoms
Objective: To investigate if patients with Parkinson’s disease (PD) undergoing subthalamic stimulation (STN-DBS) can be clustered in different subtypes based on demographic, motor and non-motor…The Critical Path for Parkinson’s Consortium approach to developing consensus recommendations for neuroimaging biomarkers appropriate for use in Parkinson’s disease drug development
Objective: To develop consensus recommendations for neuroimaging biomarkers suitable for use in Parkinson’s disease (PD) drug development. Background: Given the anticipated rise in PD prevalence…Epidemiological analysis of autosomal dominant chorea in Eastern Algeria
Objective: We aim to analyze the main epidemiological characteristics of individuals having a Huntington disease phenotype in Eastern Algeria population. Background: Huntington's disease (HD) is…Tardive dystonia manifesting in lid-opening apraxia, oromandibular dystonia, and laterocollis after long-term sulpiride use
Objective: We describe a patient who developed tardive dystonia after sulpiride treatment for over two decades. Few cases have been reported[1-3], thus we offer an…The Link between Handedness and Prevalence of Musician’s Dystonia – A Systematic Literature Review
Objective: The link between handedness and the prevalence of musician’s dystonia has not been investigated yet. In this review potential differences in handedness distribution between…Circuit-based targeting for closed-loop deep brain stimulation for Tourette Syndrome
Objective: To assess the safety, feasibility, neurophysiology and neuroimaging-driven targeting of the centromedian thalamus (CM) and anterior globus pallidus internus (aGPi) for deep brain stimulation…What change to expect in duration of benefit per dose when switching from IR CD-LD to IPX203 (ER CD-LD)
Objective: To investigate if duration of benefit (“Good On” time) per dose during immediate-release (IR) carbidopa-levodopa (CD-LD) treatment predicts response to IPX203 conversion. Background: Levodopa’s…Effects of cerebellar cTBS on motor symptoms in Huntington’s disease: a feasibility and pilot study
Objective: To evaluate the feasibility and preliminary clinical effects of a single session of cerebellar cTBS in patients with Huntington's disease (HD) with mild-moderate motor…A novel, population-specific PINK1 p.F385S loss of function mutation in an Indian family with Parkinson’s disease
Objective: To understand the molecular function of a novel missense PINK1 variant identified in an Indian family with Parkinson’s disease (PD). Background: The molecular understanding…Protective effect and mechanism of TREM2 in Parkinson’s disease with cognitive impairment
Objective: this study explored whether TREM2 plays a protective role in PD with cognitive impairment by promoting the activation of DAM. Background: The latest research…
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