Trial protocol: Randomized double blind controlled study to investigate disease modifying effect, safety and optimal dose of oral semaglutide tablet for patients with Parkinson’s disease (MOST-ABLE study)
Objective: This study aims to assess efficacy and disease modifying effect, safety, and optimal dose of oral semaglutide tablet, glucagon-like peptide-1 receptor agonists (GLP-1RAs), for…Overlapping Pathogenetic Findings in Developmental Coordination Disorder (DCD), Ataxia, Dystonia and Myoclonus: is DCD part of a Movement Disorder Spectrum?
Objective: To explore the underlying pathogenetic mechanisms of Developmental Coordination Disorder (DCD) and compare these with findings in ataxia, dystonia and myoclonus. Background: DCD is…A strategic training framework for building research capacity in the Global Parkinson’s Genetics Program (GP2)
Objective: To promote and facilitate learning internationally with resources and expertise to serve the training needs of the Global Parkinson’s Genetics Program (GP2;www.gp2.org) and its…Identifying delirium in Parkinson’s: evaluation of existing tools and measures
Objective: To evaluate the diagnostic accuracy of tools to identify delirium in inpatients with Parkinson’s disease (PD). Background: Delirium is a serious acute state of…VALIdation of models for assessing eligibility for referral for Device-Aided Treatment in Parkinson’s disease (VALIDATE)
Objective: To externally validate the Dutch Device-Aided Therapy Screening tool (D-DATS) and to compare it with the 5-2-1 criteria. Background: Timely identification of patients with…Discriminative properties and sensitivity to change of three cognitive assessment instruments in Huntington’s disease
Objective: We addressed and compared the discriminative properties of different cognitive instruments, and we determined the sensitivity to change of the proposed assessments in the…Metabolic modulation of mitochondrial DNA release in cellular models of Parkin-associated Parkinson’s disease
Objective: Our objective in this study was to elucidate the mechanisms underlying the release of mtDNA in cellular models of Parkin-associated Parkinson’s disease and to…Validation and psychometric properties of the Thai version of the hemifacial spasm grading questionnaire (HFS score) for physician-assessed clinical involvement and patient-reported health-related quality of life: a prospective observational study
Objective: The primary aim was translation to thai and cognitive debriefing of the thai version of the hfs score in patients with hfs. The secondary…Hemi-dystonia secondary to encephalitis and its response to staged pallidotomy
Objective: Reporting a case of hemi-dystonia (with involvement of trunk) secondary to encephalitis and its response to staged bilateral pallidotomy. Background: In the Axis 1…People with Parkinson’s Disease present compensatory cortical activity patterns during split-belt treadmill walking, regardless of leg or disease side dominance.
Objective: To study the effects of Parkinson’s Disease (PD) on cortical activity during split-belt (SB) walking compared to tied-belt (TB) walking, and the impact of…
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