Whole exome sequencing of 67 Swedish Parkinson patients identifies a family with VPS35 D620N
Objective: To determine the usefulness of WES in the diagnostic evaluation of Parkinson’s disease (PD) patients and to set up computational pathways for the identification…Access-PD – a ‘next generation’ registry to accelerate Parkinson’s disease research
Objective: To establish an integrated and fully remote registry for Parkinson’s disease (PD) in England, that leverages both electronic health records (EHR) and electronic patient-reported…Multiple N-of-1 trials to investigate hypoxia-based treatment in Parkinson’s disease: safety and short-term effects
Objective: In this study, we describe the safety and short-term effects of the first hypoxia-based treatment trial in Parkinson’s disease by deploying a personalized multiple…Usability of Parkinson’s KinetiGraph in deep brain stimulation for essential tremor
Objective: To estimate whether Parkinson’s KinetiGraph (PKG) can be useful in quantifying tremor severity in patients with essential tremor (ET) before and after treatment with…Integrated safety analysis of BIA-28-6156 phase 1 clinical trials (a novel allosteric activator of beta-glucocerebrosidase)
Objective: To describe the safety profile and tolerability of BIA-28-6156 observed during phase 1 clinical trials. Background: BIA-28-6156 is a novel allosteric activator of beta-glucocerebrosidase…Impact of Image-Guided Programming (IGP) in Bilateral STN Deep Brain Stimulation on Programming Time and Setting Outcomes
Objective: To determine if an image-guided programming (IGP) tool can enable shorter initial Deep Brain Stimulation (DBS) programming sessions and evaluate continued chronic use of…Sleep disorders in Parkinson’s disease patients. A case-control study.
Objective: To determine the quality of sleep, the type of sleep disorders and their correlations with motor impairment in Parkinson's disease (PD) patients. Background: Sleep…Learnings from inaugural year of foundation sponsored genetic counseling and testing program for Spinocerebellar Ataxia (SCA) types 1, 2, and 3
Objective: To describe volume, genetic results, and participant perceptions of foundation sponsored genetic counseling and testing program for SCA 1, 2, and 3. Background: Molecular…Caregiver burden in Parkinson disease: an updated scoping review
Objective: We performed a scoping review to describe caregiver burden in Parkinson disease (PD) and build on the evidence provided by Mosely at al. [1]…Combination COMT inhibitor with Levodopa reduces consumption of vitamin B6
Objective: To investigate changes in Levodopa (LD) pharmacokinetics and changes in homocysteine, vitamin B6, and vitamin B12 in Parkinson's disease (PD) patients receiving LD formulations…
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