Freezing of gait in Parkinson’s disease with glucocerebrosidase mutations: prevalence, clinical correlates and effect on quality of life
Objective: Mutations in glucocerebrosidase (GBA) can change the phenotype of Parkinson’s disease (PD). This study aimed to explore the clinical characteristics of freezing of gait…Depression in Parkinson’s disease is associated with subcortical neurodegeneration and increased risk of all-cause mortality and dementia
Objective: To evaluate the temporality, neuroanatomical correlates and prognostic significance of depression in PD using a large population cohort. Background: Depression may be an important…Fecal tyrosine decarboxylase and motor response complications in Parkinson’s Disease
Objective: To investigate the clinical correlates of gut microbe-derived tyrosine decarboxylase (tdc) and motor dysfunction in Parkinson’s Disease (PD) patients. Background: Gut microbe-derived tdc was…Altered cognitive control processes in the prodromal phase of X-linked dystonia-parkinsonism (XDP)
Objective: Investigating non-manifesting carriers (NMC) of the TAF1 gene mutation causing X-linked dystonia-parkinsonism to reveal a potential change in the neural basis of cognitive control processes during…Quantitative Evaluation of Seborrheic Dermatitis in Patients with Autonomic Dysfunction.
Objective: We quantitatively evaluated skin condition of patients with autonomic dysfunction. Background: Dyshidrosis are known to be one of autonomic symptom in Lewy body disease…Early cognitive decline in Parkinson’s disease is anticipated by enhanced frontal theta oscillations and minor hallucinations
Objective: Identify alterations associated with minor hallucinations (MH) and their role in cognitive decline in patients with Parkinson’s disease (PD) by merging electroencephalography (EEG) with…Longitudinal follow-up of pure autonomic failure with cardiac sympathetic denervation: Relevance to the body-first theory of Parkinson’s disease
Objective: In this report, we describe eight patients with PAF with nOH and imaging evidence of cardiac sympathetic denervation by 123I-metaiodobenzylguanidine (123I-MBG) single photon emission…The Comorbidity and Comedication Profiles of Patients with Progressive Supranuclear Palsy in Two German, Multicenter Cohorts: A Systematic Cross-Sectional Analysis
Objective: To investigate the pattern of comorbidities and comedications in PSP patients compared to age-matched controls. Background: Although progressive supranuclear palsy (PSP) is usually diagnosed…Laryngeal clinical biomarkers in atypical Parkinsonism – results from an international multicenter study
Objective: To investigate the prevalence of laryngeal motion abnormalities in patients with atypical Parkinsonism. Background: Using a previously published FEES task-protocol[1-3], we identified irregular involuntary…Differences in gray matter atrophy and functional connectivity between motor subtypes of Parkinson’s disease
Objective: This study compared gray matter volume (GMV) and functional connectivity among patients with Parkinson’s disease involving postural instability/gait difficulty (PD-PIGD), patients with tremor-dominant Parkinson’s disease (PD-TD) and healthy…
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