Quantification motor improvement from levodopa carbidopa infusion gel therapy in patients with Parkinson’s disease using a wearable device.
Objective: To evaluate the feasibility of using a wearable device to objectively quantify the motor improvement of a Parkinson Disease patient with a therapy modification…Spiral drawing features are similar between essential tremor and essential tremor plus
Objective: To explore the features on free hand spirals drawn by patients with essential tremor and essential tremor plus. Background: The 2018 consensus statement on…Overlapping Pathogenetic Findings in Developmental Coordination Disorder (DCD), Ataxia, Dystonia and Myoclonus: is DCD part of a Movement Disorder Spectrum?
Objective: To explore the underlying pathogenetic mechanisms of Developmental Coordination Disorder (DCD) and compare these with findings in ataxia, dystonia and myoclonus. Background: DCD is…Impact of endpoint selection on sample size calculations for disease-modifying clinical trials in Parkinson’s disease patients with GBA1 mutations
Objective: To assess clinical trial sample size estimations under variable simulated scenarios for Parkinson’s disease (PD) patients with mutations in the β-glucocerebrosidade gene (GBA1). Background:…Validation and psychometric properties of the Thai version of the hemifacial spasm grading questionnaire (HFS score) for physician-assessed clinical involvement and patient-reported health-related quality of life: a prospective observational study
Objective: The primary aim was translation to thai and cognitive debriefing of the thai version of the hfs score in patients with hfs. The secondary…MER length as a predictor of motor and non-motor outcomes of STN DBS in Parkinson’s disease
Objective: To test whether the length of the subthalamic nucleus (STN) in microelectrode recording (MER) can predict the 6-month motor and non-motor outcomes of DBS…Altered nucleus accumbens functional connectivity precedes apathy in Parkinson’s disease
Objective: To investigate whether changes in connectivity between neural regions that are associated with goal-directed behaviour predict future development of apathy in people with Parkinson’s…Progression of striatocortical dysfunction in Parkinson’s disease: a longitudinal combined PET and fMRI study
Objective: To investigate the longitudinal progression of striatal dopaminergic dysfunction and its consequences on functional connectivity (FC) networks and clinical progression in Parkinson's disease (PD)…Usability of Parkinson’s KinetiGraph in deep brain stimulation for essential tremor
Objective: To estimate whether Parkinson’s KinetiGraph (PKG) can be useful in quantifying tremor severity in patients with essential tremor (ET) before and after treatment with…Parkinson’s disease and Spatiotemporal gait parameters: A Narrative Review of Effect of Climate Changes as a Mediating Effect
Objective: This study examined the effect of climate change on spatiotemporal gait parameters in individuals with Parkinson's disease, providing insights into potential interventions to improve…
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