Decreased α-synuclein membrane-binding in the enteric nervous system as a marker of early pathology in Parkinson’s disease
Objective: The goal is to measure α-Synuclein (αSyn) membrane-binding in the enteric and central nervous system in Parkinson’s disease (PD) using both a novel, humanized…Signs of Respiratory Dysfunction across Parkinson’s Disease Spectrum
Objective: The aim of the study is to investigate signs of respiratory dysfunction across the Parkinson’s disease spectrum. Background: Respiratory dysfunction in Parkinson’s disease (PD)…Randomized, waitlist-controlled trial of Karate Intervention to Change Kinematic Outcomes in PD (KICK OUT PD)
Objective: To test the adherence to and efficacy of twice-weekly karate classes for people with mild to moderate Parkinson’s Disease (PD) on quality of life…Impact of Image-Guided Programming (IGP) in Bilateral STN Deep Brain Stimulation on Programming Time and Setting Outcomes
Objective: To determine if an image-guided programming (IGP) tool can enable shorter initial Deep Brain Stimulation (DBS) programming sessions and evaluate continued chronic use of…A rare case of PDE10A associated dystonia with bilateral striatal lesions
Objective: To describe an interesting and rare case of cervical dystonia associated with PDE10A mutation. Background: Dystonia is the third most prevalent movement disorder in…Study protocol for the iMarkHD study in individuals with Huntington’s disease
Objective: To describe the study protocol for the iMarkHD study. Background: Huntington’s disease (HD) is still often defined by the onset of motor symptoms, inversely…Asian LRRK2 variants do not increase Likelihood Ratios derived from MDS prodromal Parkinson’s Disease criteria in a community population
Objective: To determine if the presence of the Asian LRRK2 risk variants (G238R, S1647T, R1628P) confers an increased risk in developing PD in a Singaporean…Using Long read sequencing to identify complex structural variants in PRKN-PD
Objective: Identify complex structural variants in PRKN gene from Parkinson’s disease patients. Background: PRKN is the most frequent causative gene in young onset Parkinson's disease…Pilot study of outpatient rehabilitation of patients with Huntington’s disease in Russia
Objective: The benefits of exercises and physical activity in Huntington's disease in terms of motor function, gait speed, and balance, as well as a range…Hemifacial Spasm: Recent experience in a movement disorders reference center in Chile
Objective: To analyze the demographic characteristics of patients with HFS and their response to different BoNT at the center for movement disorders CETRAM in Santiago,…
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