Post stroke Restless Limb Syndrome and its impact on sleep and life quality in patients in Rural Gujarat, India
Objective: We aimed to assess the prevalence of RLS in patients with brain stroke and assess its impact on sleep and quality of life. We…A novel missense variant in the TTBK2 gene in a north American family with late-onset cerebellar ataxia.
Objective: To describe a case of novel genetic variant of TTBK2 gene in a woman with late-onset cerebellar ataxia and her symptomatic mother. Background: Pathogenic…Self-perception of symptoms lateralization and association with symptoms severity in Parkinson’s disease.
Objective: To compare the self-perception of symptoms lateralization with clinical evaluation, and explore associations with symptoms severity, onset side, and handedness. Background: Symptoms lateralization is…A multicenter, matched case-control study of alpha-synuclein accumulation in the gastrointestinal tract of Parkinson’s disease
Objective: 1) To determine the possibility as a pathologic biomarker of alpha-synuclein (AS) accumulation in the gastrointestinal (GI) tract in patients with Parkinson’s disease (PD) and…Evaluation of Cognitive Assessment Tools in Parkinson’s Disease
Objective: To evaluate a variety of cognitive assessment scales in a longitudinal Parkinson’s disease (PD) cohort. Background: Cognitive impairment is one of the most common and…Psychosocial factors impacting participation in a time-intensive deep brain stimulation study of individuals with Parkinson’s disease and dystonia
Objective: To evaluate psychosocial factors impacting the number of hours of participation in the first five months of a time-intensive deep brain stimulation (DBS) study.…Therapeutic Plasma Exchange in the Management and Outcome of Stiff-Person Syndrome: A Systematic Review
Objective: In this review article, we'll explore TPE's role in treating Stiff Person Syndrome(SPS) and its outcomes. Background: Rigidity, stiffness, and intermittent spasms of the…A comparative study of non-motor symptoms in Huntington’s disease and Parkinson’s disease
Objective: To assess and compare the non-motor symptoms (NMS) profile in Parkinson's disease (PD) and Huntington's disease (HD) patients using Parkinson's Disease Non-Motor Symptom Rating…Investigating glutamate toxicity associated to Park2 mutations in pre-clinical models of Parkinson’s Disease
Objective: To generate and characterize induced pluripotent stem cells (iPSCs)-derived in vitro cellular models of Autosomal Recessive Juvenile Parkinsonism (ARJP) carrying Park2 mutations with a…Estrogen and progesterone influence membrane functions and glucose transporter expression in synaptosomes of different age groups of naturally menopausal rats
Objective: The objective of this study was to determine the effect of 17 β-estradiol (E2) and progesterone (P4) on the activities of Na+ K+ ATPase, monoamine…
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