A Review of the Genetic Spectrum of Hereditary Spastic Paraplegias in the Middle East and North Africa Region
Objective: To systematically review existing literature and collect data on Hereditary Spastic Paraplegias(HSP) in the Middle East and North Africa(MENA), aiming to assess the prevalence…Clinical and Genetic Characteristics in a Chinese Cohort of Complex Spastic Paraplegia Type 4
Objective: To delineate the genotypic and phenotypic spectrum of patients with complex SPG4 phenotype and further explore genotype-phenotype correlations. Background: Spastic paraplegia type 4 (SPG4),…Efficacy and Safety of DaxibotulinumtoxinA-lanm for Injection in Adults with Cervical Dystonia: Pooled Global Analysis of ASPEN-1 and ASPEN-1-CN
Objective: To evaluate the pooled efficacy and safety of 2 doses of DaxibotulinumtoxinA-lanm for injection (DAXI) for the treatment of cervical dystonia (CD) in 2…Clinical Outcomes and Local Field Potential Characteristics in Bilateral GPi DBS in 2 cases of X-Linked Dystonia Parkinsonism
Objective: We describe clinical outcomes and local field potential characteristics in 2 cases of fulminant onset XDP who went on to have bilateral GPi DBS…A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of OnabotulinumtoxinA for the Treatment of Upper Limb Essential Tremor: ELATE Trial
Objective: Here, we present the eligibility criteria and study design of ELATE, a Phase 2b clinical trial evaluating the safety and efficacy of onabotA compared…Association of cognition and other clinical characteristics of individuals with Essential Tremors
Objective: To examine the correlation between cognition and other clinical characteristics (motor and non-motor) in people with Essential Tremor. To examine the correlation between cognition and…Deep Brain Stimulation in Tourette Syndrome: Characteristics of Three Patients Pre and Post Implantation
Objective: To elucidate how deep brain stimulation (DBS) for Tourette’s syndrome (TS) impacts psychiatric comorbidities including attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety, and depression.…Functional neurological disorders might be a frequent cause of slow orthostatic tremor: insights from a case series.
Objective: To study the clinical and electrophysiological characteristics of series of patients with slow orthostatic tremor (sOt) Background: sOT is characterized by tremor <13Hz affecting…Is essential tremor-plus phenotype a prodromal phase of Parkinson’s disease ?
Objective: To study the probability of conversion of essential tremor (ET) and ET-plus patients to Parkinson's disease (PD). Background: ET-plus syndrome represents a wide spectrum…How Common is Essential Tremor in Germany? A Real-World Claims Data Analysis
Objective: To estimate the prevalence and incidence of essential tremor (ET) stratified by age and sex, using insurance claims data from a large representative [1,2]…
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