Curved Trajectories in Stereotactic Neurosurgery
Objective: To develop a system that permits remotely navigated curved trajectories of stereotactic electrodes Background: Stereotactic neurosurgery is restricted to linear trajectories. This limits flexibility…A tau-directed monoclonal antibody could alter the tau pathology of progressive supranuclear palsy
Objective: The purpose of this study is to examine the modification of tau pathology in brain regions of a patient with progressive supranuclear palsy (PSP)…Leveraging MRI and machine-learning for early detection of cognitive impairment in Parkinson’s disease
Objective: To develop a machine learning model using MRI data that predicts the likelihood of cognitive impairment in newly diagnosed patients with Parkinson's disease (PD).…A staged screening paradigm to identify people at risk of Parkinson’s disease in the Parkinson’s Progression Markers Initiative
Objective: To identify people at risk of Parkinson’s disease (PD) using a staged-screening paradigm. Background: Early recognition of people with PD may be essential to…A Parkinson’s Manifesto for Europe
Objective: To collate the wishes and ambitions of the Parkinson’s community in Europe and create a guide for those working in health care, research and…Genetic and phenotypic characterization of ATX-FAT2 (SCA45) in three Indian families
Objective: Delineation of clinical and genetic features of Spinocerebellar ataxia 45 (SCA45) in three families of Indian origin. Background: SCA45 has been reported in few…Disease progression in Parkinson‘s disease patients with Mild Cognitive Impairment: 5-year longitudinal study from The Early Parkinson’s disease Longitudinal Singapore (PALS) cohort
Objective: To investigate motor, non-motor and cognition progression in early PD patients with Mild Cognitive Impairment (MCI) and normal cognition over 5 years. Background:…Questionnaire for the detection of Parkinson’s disease
Objective: The aim of this study was to develop a questionnaire for detecting Parkinson's disease in its early stages and to evaluate its effectiveness. Background:…Use of levodopa-carbidopa intestinal gel to treat a patient with multiple system atrophy (MSA)
Objective: To describe a case report on the use of Levodopa-carbidopa intestinal gel (LCIG) to treat non-motor symptoms in a patient with multiple system atrophy (MSA) Background: There is no…Testing for alcohol responsivity in familial essential tremor
Objective: In this study, we describe the alcohol response in our familial essential tremor cohort by employing the Knudsen-Lorenz-Deuschl test for alcohol responsivity outside its…
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