The efficacy of tremor detection and suppression device in intractable rest tremor in patients with Parkinson’s disease
Objective: This study was designed to determine the efficacy of the Tremor Detection and Suppression device (TDS) as a therapeutic option in PD patients with…A phase II, pragmatic, randomized clinical trial on a high-intensity exercise and fall prevention boot camp for Parkinson’s disease: Signal of efficacy
Objective: To determine if a high intensity exercise and fall prevention boot camp (HIBC) would produce greater benefit than a low intensity control (Fitness Counts…Best supportive care or palliative care for late stage Parkinsonian syndromes?
Objective: To ask whether best supportive care might be more suitable for patients with Parkinson's disease (PD) and Parkinsonian syndromes and their family than palliative…Hospitalisation following different initial therapies in early Parkinson’s disease: Analysis of hospital episodes statistics from the PD MED EARLY trial
Objective: To compare hospitalisation rates of Parkinson's disease (PD) patients randomised between three different classes of oral medications used for early PD treatment. Background: PD…A randomized controlled clinical study to evaluate efficacy, safety and tolerability of SC L-dopa/carbidopa (ND0612H) infusion regimens in fluctuating PD patients
Objective: To evaluate the efficacy, safety & tolerability of continuous subcutaneous infusion regimens of ND0612H. Background: L-dopa remains the most effective PD medication, however oral…A combined therapeutic approach in the management of abnormal postures in Parkinson’s disease
Objective: To confirm the role of external oblique muscles (EO) in upper Camptocormia (CC) and Pisa Syndrome (PS) and evaluate the beneficial effect of a…Continuous subcutaneous delivery of solubilized carbidopa improves the pharmacokinetic profile of levodopa
Objective: To characterize the peripheral pharmacokinetics and CNS metabolism of levodopa during continuous subcutaneous delivery of solubilized carbidopa. Background: Although many commercial levodopa formulations include…Association of Parkinson’s disease with essential tremor
Objective: In this study we present the clinical characteristics of 10 patients (6 males, 4 females) with both essential tremor (ET) and Parkinson's disease (PD).…Can treadmill training facilitate the dual-task gait in Parkinson’s disease?
Objective: Investigate the effects of a single session of treadmill gait training combined with cognitive tasks on dual-task gait in Parkinson's disease. Background: The loss…The potential therapeutic effect of intranasal administration of stem cells in rotenone model of Parkinson’s disease in mice
Objective: In this study we assessed the potential beneficial effect of intranasal administration of mesenchymal stem cells (MSCs) to rotenone model of PD in C57bl/6…