Alterations in muscle synergies in early stage Parkinson’s disease
Objective: Identify whether muscle synergies are altered in stage I Parkinson's disease (PD). Background: Muscle synergies have been proposed as a mechanism utilized by the…In vivo MRI detection of Parkinson’s disease associated degeneration in the lateral ventral tier of substantia nigra pars compacta
Objective: To test a novel multimodal MRI approach for in vivo assessment of the subregion of substantia nigra pars compacta (SNpc) most vulnerable to Parkinson's…Lessons-experienced in the creation of a global public-private consortium with the goal of advancing treatments that hold most potential for delayed disease progression in Parkinson’s disease – Critical path for Parkinson’s (CPP)
Objective: The path is summarized that led to the creation of a global public-private-partnership uniting an international non-profit charity, Parkinson's UK, a global non-profit organization,…Detection of primary olfactory cortex dysfunction in early-stage Parkinson’s disease
Objective: To detect the functional changes of primary olfactory cortex (POC) in the early-stage Parkinson's disease (PD) using functional magnetic resonance imaging (fMRI). Background: Olfactory…Assessment of brainstem function with blink reflex variations in Parkinson’s disease
Objective: To assess the brainstem function with different variations of blink reflex studies in Parkinson's disease (PD). Background: Although PD presents principally as a movement…Substantia nigra hyperechogenicity in Mexican patients with Parkinson’s disease
Objective: To determine the prevalence of increased echogenicity in the substantia nigra in patients diagnosed with idiopathic Parkinson's disease at the University Hospital "Dr. José…A longitudinal study of functional deterioration of primary olfactory cortex in early-stage Parkinson’s disease
Objective: To study the dynamic changes of the olfactory cortex function in the early-stage Parkinson's disease (PD) using functional magnetic resonance imaging (fMRI). Background: Olfactory…Impact of datscan on clinical decision making: diagnosis and management of clinically uncertain Parkinsonian syndromes
Objective: To assess changes in clinical diagnosis and/or treatment of 200 consecutive patients with clinically uncertain Parkinsonian syndromes who underwent DaTscan imaging with ioflupane for…Effects of zonisamide on dementia with Lewy bodies (DLB): A post-hoc analysis of phase 2 study for parkinsonism in DLB patients
Objective: To clarify the effects of zonisamide (ZNS) on the core symptoms of dementia with Lewy bodies (DLB), we performed a post-hoc analysis using data…Cognitive development in individuals with mild Parkinsonian signs
Objective: With this study we aimed to prospectively evaluate the development of cognitive performance in individuals with persistent Mild Parkinsonian Signs (MPS) compared to neurologically…