Corpus callosum thickness and area in Parkinson’s disease
Objective: To evaluate corpus callosum thickness and area in Parkinson's disease (PD) subjects and the relationship of these measures with cognitive impairment. Background: Many PD…Influence of different spike sorting algorithms on the detection of single unit spiking activity in the subthalamic nucleus of patients with Parkinson’s disease
Objective: To determine the most suitable spike sorting algorithm for intraoperatively recorded extracellular currents in the subthalamic nucleus (STN) of patients with Parkinson's disease (PD).…Negative emotional signals impair isometric force control in Parkinson’s disease
Objective: To investigate the effect of sustained exposure to negative emotional stimuli on isometric grip-force control in Parkinson's disease (PD). Background: Recent animal studies have…Metabolic brain changes related to specific cognitive impairment in non-demented Parkinson’s disease patients
Objective: To measure the expression of the Parkinson's disease related cognitive pattern (PDCP) in 18F-FDG-PET brain images of Parkinson's disease (PD) patients and healthy controls…The feasibility of measuring fatigability in early-stage Parkinson’s disease using functional MRI
Objective: To investigate the effect of fatiguability on brain activation in people with Parkinson's (PwP) in comparison with healthy volunteers(HV). Background: Fatiguability, an objective decline…The relationship among clinical features, DAT scintigraphy and MIBG cardiac scintigraphy in patients with Parkinson’s disease
Objective: The aim of this study is to evaluate correlations among clinical features of Parkinson's disease (PD), odor stick identification test for Japanese (OSIT-J) score,…Ultra high field magnetic resonance imaging of nigrosome 1 is a biomarker of new onset and premotor Parkinson’s disease
Objective: An unmet need exists to develop a methodology to diagnose Parkinson's disease (PD) in the premotor stage, so that patients can be enrolled in…Intraoperative localization of beta band and high-frequency oscillations within the subthalamic nucleus
Objective: To investigate whether beta band activity (13-30Hz) and high-frequency oscillations (150-400Hz) arise from the same spatial location within the subthalamic nucleus (STN) of Parkinson's…The patient’s perspective: The effect of dopamine on Parkinson symptoms
Objective: To investigate the correlation between patient-based vs. clinician-based L-Dopa effects on PD symptoms in tremor-dominant patients. Background: Medication adjustments are often solely based on…Detecting brainstem changes in Parkinson’s disease using quantitative MRI
Objective: 1. Can brainstem changes be detected using quantitative MRI (qMRI). 2. How many subjects would be required to detecting changes in brainstem regions affected…