Higher risk of cognitive impairment in Parkinson’s disease with comorbid diabetes
Objective: To determine the risk of cognitive impairment in individuals with Parkinson’s disease (PD) and diabetes. Background: Diabetes is associated with risk of cognitive impairment…Depression and Cognitive Performance in Patients with Parkinson’s Disease
Objective: The aim of this study was to assess the relationship between depression on cognitive performance in Parkinson’s disease patients. Background: There are very few…TMEM230 mutation analysis in Parkinson’s disease in a Chinese population
Objective: To investigate the prevalence of TMEM230 mutations in Chinese patients with familial and sporadic PD. Background: Recently, Hanxiang Deng and colleagues identified a missense…Higher genetic load is associated with an earlier disease onset but not with more rapid disease progression in Parkinson’s disease
Objective: To evaluate the influence of genetic variants on phenotypic variability and disease progression in PD patients. Background: Parkinson’s disease (PD) patients show a large…Understanding the role of LRRK2 in Indian population
Objective: Genomic approaches in Caucasian population show little transferability to other ethnically diverse populations such as Indian population. Understanding the genetic architecture of a disease…Assessing the response to L-dopa/carbidopa intestinal gel infusion (Deudopa) based on genetic status.
Objective: To asses genetic impact on dosage of L-dopa/carbidopa treatment Background: L-dopa/carbidopa intestinal gel infusion (LCIG) is a method of continuous dopaminergic stimulation used in…Genotype-phenotype correlations in Parkinson disease patients who carry mutations in the GBA gene.
Objective: To assess genotype-phenotype relationship between mild and severe GBA mutation carriers among patients with Parkinson's disease Background: Mutations in the Glucocerebrocidase gene (GBA) are…Comparison of the non-motor symptom assessment scale between LRRK2 G2019S positive versus matched control Parkinson disease
Objective: To compare the non-motor symptom assessment scale (NMSS) score between Leucine-rich repeat kinase 2 (LRRK2) mutation carriers with Parkinson disease (PD) and matched controls with…Patient-derived GBA1-PARK2 double-mutant cellular models to study the effect of GBA1 as a modifier of familial Parkinson’s disease
Objective: In this study, we propose to decipher the role of GBA1 as a modifier of familial Parkinson’s disease (PD) using double-mutant patient-derived cellular models…Caffeinated Drinks, LRRK2 Genotype and PD
Objective: To determine the role of caffeine containing drinks on penetrance in LRRK2-associated PD Background: LRRK2 penetrance is reduced for PD [1]. Environment and/or other…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.