Stiff person syndrome: Case series
Objective: To report and discuss three cases of Stiff Person Syndrome (SPS) with distinguished clinical features. Background: SPS is a rare disorder characterised by progressive…Is physiotherapy an effective for treatment of Parkinson’s disease?!
Objective: Aim of investigation was to evaluate the effectiveness of physiotherapy intervention compared with no intervention in patients with PD. Background: In spite of various…Efficacy and safety of tetrabenazine in hyperkinetic movements disorders- An observational study
Objective: To assess the efficacy and side-effects of TBZ in Huntington disease (HD), vascular chorea, tics, dystonia, oromandibular dyskinesia and other tardive syndromes (TS). Background:…Diverse effects of alpha-synuclein fibrils on various neuron cell lines, using different buffers
Objective: To investigate the neurotoxic properties of alpha-synuclein (α-Syn) aggregation in different buffers including PBS, SBF and Tris on altered cell lines, SHSY5Y, SK-N-MC and…Diagnostic value of a new coronal examination plane in transcranial nigral sonography and of additional M-mode tremor frequency determination for the differentiation of idiopathic Parkinson’s disease and essential tremor
Objective: To (1) evaluate a new coronal examination plane in comparison to the established axial examination plane for detection of nigral hyperechogenicity and (2) to…Real-life data on the use of levodopa carbidopa intestinal gel in Parkinson’s disease
Objective: To report our institution's initial clinical experience with initiation and management of levodopa carbidopa intestinal gel (LCIG) formulation Duopa®. Background: Carbidopa/levodopa intestinal gel (LCIG)…Inhibition of glucosylceramide synthase reduces pathology and improves cognition in synucleinopathy murine models
Objective: We investigated the merits of glucosylceramide synthase (GCS) inhibition as a potential treatment for synucleinopathies. Background: Mutations in GBA, the gene encoding glucocerebrosidase, are…Correlation between Parkinson’s disease and malignant tumors
Objective: We have carried out the research among the group of Sardinian patients with PD, led by our Ambulatory of Movement Disorders, to evaluate the…Real world conversion of levodopa to a novel extended release levodopa preparation: Determining predictors and dose ratios
Objective: To determine predictors of response and conversion ratios for a novel extended release levodopa preparation. Background: A new extended release levodopa preparation, Rytary®, has…Virtual-reality balance training with Nintendo-Wii games improves dynamic balance in Parkinson’s disease patients
Objective: This study was to investigate the effectiveness of a 8-week virtual reality exercise program designed around the Nintendo Wii (Wii), in improving balance among…