A cognitive fMRI study of non-manifesting LRRK2 and GBA carriers
Objective: To assess the cognitive profile of non-manifesting carriers of GBA and LRRK2 mutations using two fMRI tasks: a Stroop interference and N-Back working memory…The association between structural brain connectivity with plasma APO-A1 levels in Parkinson’s disease: Connectometry approach
Objective: Features of the lipid profile specially cholesterol levels are association with PD risk. However no such data exists on the association of these plasma…Cortical atrophy in cognitively impaired Parkinson’s disease patients
Objective: To explore whether cognitive impairment in Parkinson's disease (PD) patients is associated with cortical thinning. Background: Parkinson's disease (PD) affects 1% of those over…The role of cathepsin L involved in the activation of microglia and Parkinson’s disease
Objective: To investigate the role of lysosomal protease cathepsin L in the activation of microglia and the injury of dopaminergic neurons, and further to interpret…Transcranial sonography of the substantia nigra and its correlation with iron metabolism and c-reactive protein in Parkinson’s disease
Objective: To measure the echogenicity of the substantia nigra (SN) by transcranial sonography (TCS) in PD patients and discuss its correlation with iron metabolism and…DAT SPECT data of Parkinson’s disease patients with and without REM Sleep Pathology: A report from the DeNoPa cohort
Objective: To evaluate the DAT SPECT (Single photon emission computerized tomography of the dopamine transporter) parameters for Parkinson's disease (PD) patients with REM Sleep Behavior…Functional connectivity underpinnings of fatigue in “drug-naïve” patients with Parkinson’s disease
Objective: Using resting-state functional MRI, we investigated the functional correlates of fatigue in a cohort of “drug-naïve”patients with PD. Background: Fatigue is a common problem…Motor subtypes in Parkinson’s disease are distinguished by alterations in morphology and white matter integrity
Objective: This study aimed to extend current knowledge on symptomatic heterogeneity in Parkinson's disease (PD) by investigating structural alterations underpinning FC. Background: The postural instability…Prognostic factors of motor symptoms in Parkinson’s disease using neuromelanin imaging and the relationship with (123)I-FP-CIT-SPECT
Objective: This study aimed to examine the relationship between findings of neuromelanin sensitive MRI findings and motor complications. We also examined the correlation of findings…Dynamic dopamine transporter images are helpful for diagnosing parkinsonism
Objective: This study is aimed at introducing a new method to get Dopamine transporter (DAT) imaging simultaneously with regional cerebral flow (CBF) imaging. Background: DAT…