Early grey matter changes in structural covariance networks in Huntington’s disease
Objective: To identify network integrity changes in Huntington's disease (HD) using grey matter whole brain structural covariance networks and to examine relationships between anatomical networks…Progression of motor subtypes in Huntington’s disease: A six-year follow-up
Objective: To investigate the course of motor symptoms in Huntington's disease (HD) and their relationship with cognitive- and general functioning over time. Background: The motor…Dysphagia in early stage Huntington’s disease (HD) – Pilot observations from a multimodal imaging study
Objective: To assess the central neural control of swallowing in HD patients with mild dysphagia using a multimodal imaging approach combining qualitative and quantitative swallowing…Abnormal intrinsic brain activity reveals neural correlates of impaired cognitive function in early stage of Huntington’s disease (HD): A resting-state fMRI study
Objective: To better understand the mechanism underlying cognitive impairment in HD. Background: Cognitive impairment can precede the motor symptoms and deteriorates over time in HD…Cognitive impairment in Huntington’s disease
Objective: The present study was done to assess cognitive impairment in HD patients using a neuropsychological battery and to correlate with clinical severity and CAG…Verbatim patient-reported outcomes and trails making test B (TMT-B) performance in the REACH2HD trial
Objective: Examine the relationship between Trails Making Test B (TMT-B) performance and bothersome cognitive complaints among Huntington Disease (HD) research participants in the REACH2HD randomized-controlled…Cortico-striatal functional connectivity in the premanifest and manifest period of Huntingtons disease measured with high-field functional magnetic resonance imaging
Objective: To assess functional connectivity in the premanifest and manifest period of Huntington's disease (HD) by using functional Magnetic Resonance Imaging (fMRI) at high-field (7…Striatal molecular alterations in Huntington’s disease gene expansion carriers: A systematic review and meta-analysis of PET studies
Objective: To systematically examine the evidence of striatal molecular alterations in premanifest and manifest Huntington's disease gene expansion carriers (HDGECs) as measured by Positron emission…Tau pathology in Huntington’s disease: A brief in vivo PET-imaging report
Objective: To assess feasibility of measuring pathological tau deposition in patients with Huntington's disease (HD) using [18F]-AV-1451 (f.k.a. T807) PET. Background: HD is a progressive…Dysregulations of GABAergic neurotransmission in Huntington’s disease brain
Objective: To investigate (1) the expression of GABAA receptors and KCC2 in both Huntington's disease (HD) mouse models and patients and (2) the inhibitory effect…