Increased anti-MAG autoantibodies titers in Parkinson’s disease
Objective: To search for biomarkers of neurodegenerative process in Parkinson's disease (PD).There is emerging evidence that humoral response may be involved in the pathogenesis and…Toward a new biomarker on Parkinson’s disease: Study of alpha synuclein on upper enteric system by endoscopy
Objective: The aim of our study was to investigate the alpha synuclein deposition at the enteric nerve system on patient with Parkinson's disease and provide…Alpha-synuclein in gastric and colonic mucosa in Parkinson’s disease: Limited role as a biomarker
Objective: We aimed to investigate the utility of alpha-synuclein (α-SYN) immunoreactivity from gastric and colonic mucosal tissues obtained by routine endoscopy to detect Parkinson's disease…Longitudinal measurements of cerebrospinal fluid biomarkers in Parkinson’s disease
Objective: To investigate whether cerebrospinal fluid (CSF) levels of tau, phosphorylated tau, β-amyloid42, α-synuclein, neurofilament light and YKL-40 change over time and if changes correlate…Objective methods for quantifying the deep brain stimulation (DBS) efficacy in subthalamic-nuclei (STN) neurons with microelectrode recording (MER) technology
Objective: To design a computational modeling to develop a new diagnostic tool for effective neuro-medical-diagnostics for end users, to investigate and evaluate the potential benefits…Counteracting PINK1/parkin deficiency by activating alternative mitophagic pathway: a potential therapeutic intervention for Parkinson’s disease
Objective: To identify a new therapeutic target for developing neuroprotective treatment in Parkinson's disease (PD) by improving mitochondrial function through restoration of mitochondrial quality control…Physical training prevents depressive-like behavior and bdnf decrease in an animal model of Parkinson’s disease
Objective: The aim of this study was to investigate the effects of two types of physical training on depressive-like behavior and pro-BDNF, BDNF and its…Speed and severity of toxicity induced by pre-formed α-synuclein fibrils in rat brain is enhanced by α-synuclein overexpression
Objective: To develop a physiologically relevant model of PD. Background: Intracerebral injection of pre-formed α-synuclein fibrils has emerged as an interesting tool to induce PD-like…SOD1 aggregation: A pathological link between Parkinson’s disease and amyotrophic lateral sclerosis?
Objective: To characterize (1) a novel association between superoxide dismutase 1 (SOD1) aggregation and neuronal loss in the Parkinson's disease (PD) brain and (2) the…Cerebellar atrophy in Parkinson’s disease and its implication for network connectivity
Objective: To determine the effect of cerebellar atrophy on resting-state network abnormalities in individuals with Parkinson's disease. Background: In Parkinson's disease, the cerebellum is a…