Depression, anxiety, and apathy in Parkinson’s disease: Insights from neuroimaging studies
Objective: (1) To evaluate the existing neuroimaging studies of depression, anxiety and apathy in Parkinson's disease (PD) and (2) to determine the key neural pathway…Longitudinal assessment of sleep in an incident Parkinson’s disease cohort
Objective: To evaluate subjective and objective measures of sleep disturbance in an incident PD cohort over longitudinal follow-up. Background: Sleep disturbance is widely recognised as…Retinal nerve fiber layer thinning: A window into rapid eye movement sleep behavior disorders in Parkinson’s disease
Objective: To determine whether retinal structures are altered with the onset of rapid eye movement (REM) in Parkinson's disease (PD). Background: Rapid eye movement (REM)…Emotional valence and arousal ratings from rewarding and fearful stimuli are not influenced by levodopa in Parkinson’s disease
Objective: To analyze the effects of levodopa on affective ratings of emotional valence and arousal to rewarding, fearful and neutral stimuli in PD patients and…P100 latency of pattern reversal visual evoked potential and visual hallucination in Parkinson’s disease
Objective: To investigate whether P100 latency of pattern reversal visual evoked potential (PR-VEP) can predict the development of visual hallucination (VH) in Parkinson's disease (PD).…Impaired color discrimination selectively associates with postural instability and gait difficulties in Parkinson’s disease
Objective: To investigate the relationship between impairments of the cardinal motor impairments and color discrimination deficits in Parkinson's disease (PD). Background: Previous studies have shown…Anosmia predicts development of more severe motor symptoms including freezing of gait and impaired balance at 2 year follow-up in PD
Objective: To investigate the relationship between baseline anosmia and 2-yr interval development of motor impairments in Parkinson's disease (PD). Background: More severe olfactory deficits have…Clinical profile of Parkinson’s disease at the neurology department of Point G Teaching Hospital
Objective: To determine the frequency and clinical features of PD at the neurology department of Point G Teaching Hospital. Background: PD results from loss of…Quality of life after subthalamic stimulation depends on non-motor symptoms in Parkinson’s disease
Objective: To investigate non-motor symptoms (NMS) to find contributing factors for quality of life (QoL) outcome after subthalamic nucleus (STN) deep brain stimulation (DBS) in…Evolution of mild Parkinsonian signs in a longitudinal population-based cohort
Objective: To investigate evolution of mild Parkinsonian signs (MPS) in an ongoing longitudinal study on Parkinson's disease (PD). Background: Mild motor impairmant may progress to…