Peri-operative dopaminergic replacement protocol with rotigotine in Parkinson’s disease patients
Objective: To evaluate the accomplishment of a peri-operative dopaminergic replacement protocol established in our centre from 2011 to 2014, and analyse the main factors associated…Group climate in the voice therapy of patients with Parkinson’s disease
Objective: To examine the impact of coaching and group dynamics activities in the voice, speech and communication of Parkinson's disease (PD) patients, as well as…Speech and voice range profile in patients with Parkinson’s disease with deep brain stimulation: Preliminary data
Objective: To assess the use of Voice Range Profile(VRP) and Speech Range Profile(SRP) in the evaluation of patients with on and off Deep brain stimulation(DBS).…Effect of over(exaggerated) articulation technique in voice and speech of individuals with Parkinson’s disease with deep brain stimulation
Objective: To investigate the immediate effect and after 15minutes(min) of over articulation technique in individuals with Deep Brain Stimulation(DBS). Background: Studies evaluating the immediate effects…Preclinical evaluation of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias: Is it a ‘chemical’ DBS?
Objective: To evaluate mechanism of long-term activity of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias (LID). Background: Ketamine is an anesthetic that, when administered as…The clinical effects of mucuna and green tea in combination with levodopa-benserazide in advanced Parkinson’s disease: Experience from a case report
Objective: To describe the clinical effects of combined natural dopaminergic drugs with conventional levodopa therapy in a PD patient with motor and non-motor complications. Background:…Effect of pharmacist-led interventions on motor symptoms and quality of life in Parkinson’s patients: A pilot study
Objective: Improvement of on-off symptoms in ambulatory patients with Parkinson's disease (PD) by introduction of a multi-faceted medication optimization program. This consisted of a patient…Novel small molecules targeting alpha-synuclein aggregation for the treatment of Parkinson’s disease
Objective: To develop novel, small molecular weight compounds, that can interfere with the aggregation process of alpha-synuclein (aSyn), as disease modifying agents. Background: The aggregation…Therapy escalation in Parkinson’s disease – The TEMP trial, a regional survey
Objective: To assess socio-demographic and disease specific data in patients with Parkinson's disease (PD) before and one year after therapy escalation with subcutaneous apomorphine (APO),…Upper limb motor tests are related to clinical ratings of motor function in advanced Parkinson’s disease
Objective: The aim of this study was to investigate whether upper limb motor tests are related to clinical ratings of motor function in Parkinson's disease…