Beyond 30 years of Parkinson’s disease: A comprehensive characterization of long-surviving patients
Objective: To analyze the features of very late stage Parkinson's disease (PD) in a selected group of patients treated with bilateral subthalamic nucleus DBS (STN-DBS),…Biochemical features of lipids spectrum in blood in patients with Parkinson’s disease
Objective: To study characteristic of lipid levels in patients with PD. Background: Currently, there is no clear data about the features of lipid metabolism in…How accurate is the prediction of driving ability in a Parkinson’s clinic setting?
Objective: To determine whether routine clinical assessment (motor examination, cognitive assessment and global clinical impression) accurately predicts the ability of People with Parkinson's (PwP) to…Examining the clinical profile of nelotanserin, a novel agent in development for Lewy body dementia
Objective: To examine the clinical profile of nelotanserin, a novel agent in development for the treatment of Lewy body dementia. Background: Although not FDA-approved for…Psychogenic non-epileptic seizures among patients with temporal lobe and other epilepsies: Phenomenology and EEG correlates
Objective: To determine the extent to which cortical epileptic foci of patients with comorbid psychogenic non-epileptic and epileptic seizures (PNES/ES) differ from age- and gender-matched…Combinative therapy of memantine and galantamine hydrobromide as a tool of choice for the treatment of vascular parkinsonism with early appearance of dementia symptoms
Objective: Our primary aim was comparative study of monotherapy with memantine and combinative therapy with memantine and galantamine hydrobromide for treatment of vascular parkinsonism with…The neurosteroid dehydroepiandrosterone sulfate (DHEAS) reverses the dopaminergic deficiencies in mild hepatic encephalopathy: A possible therapeutic issue for the management of parkinsonism in cirrhotic patients
Objective: In the present study, we describe the changes of the dopaminergic system occurring in the cirrhotic rats and concomitantly we investigated the effect of…Curcumin supplementation improves motor dysfunction in lipopolysaccharide induced Parkinon’s disease model: Possible biochemical, neurochemical and immunohistochemical alterations in rats
Objective: In the present study potential neuroprotective effects of curcumin were tested to determine if they could help to minimize microglia–mediated damage in single intranigral…Sensorimotor impairments and the excitability of spinal cord in lead intoxicated rat during development and a potent restorative effect of curcumin
Objective: In this study we firstly investigated the effect of prenatal exposure of rats to lead (3g/l) from neonatal to adult age, on the motor/sensory…Role of the atypical vesicular glutamate transporter VGLUT3 in l-DOPA-induced dyskinesia
Objective: To evaluate the role of the atypical vesicular glutamate transporter 3 (VGLUT3) and the vesicular acetylcholine transporter (VAChT) in L-DOPA-induced dyskinesia. Background: Parkinson's disease…