TMS-EEG markers of inhibitory deficits in Huntington’s disease
Objective: Given the GABAergic nature of TMS-evoked EEG activity, we tested whether GABAergic deficits in Huntington's disease (HD) patients produce any significant change in TMS-EEG…Automatic event-detection for the neurophysiological evaluation of voluntary and involuntary movements
Objective: This project aims at creating a tool for automatic EMG event- detection to support clinicians in this process. Background: Neurophysiological evaluation of voluntary and…Motor cortex neuroplasticity and learning following high-intensity interval exercise
Objective: To determine the effect of high-intensity interval (HIT) exercise on motor cortex plasticity and learning in healthy young adults. Background: Motor skill learning requires…Mirror movements in Moebius syndrome: Mirroring beyond movements
Objective: To understand pathophysiology of mirror movements (MM) in Moebius syndrome patients by performing comprehensive neurophysiologic studies in two patients. Background: MM are involuntary movements…Selective activation of excitatory cell groups in the medial medulla differentially affects spatial-temporal gait parameters
Objective: To study the role of excitatory neurons in the ventromedial medulla in gait using Designer Receptors Exclusively Activated by Designer Drugs. Background: The medial…Refined basal ganglia model accounting for GPi modulation of thalamic tonic and burst modes
Objective: To test our hypothesis that a principal role of GPi GABAergic output is to regulate the dual burst and tonic modes of thalamocortical neurons.…PET examination of the monoamine transporter with 11C-beta-CIT
Objective: To investigate the utility of 11C-β-CIT PET scan on Parkinson's disease diagnosis. Background: The monoamine reuptake sites transport dopamine, noradrenaline and serotonin from the…Relation between the clinical features and the standardized heart to mediastinum ratio in cardiac metaiodobenzylguanidine imaging in patients with Parkinson’s disease: A multicenter cross-sectional study
Objective: To investigate relation between the clinical features and the standardized heart to mediastinum (H/M) ratio by cardiac metaiodobenzylguanidine (MIBG) imaging in patients with Parkinson's…Excessive daytime sleepiness is mediated by loss of caudate dopaminergic function in Parkinson’s disease
Objective: To investigate whether excessive daytime sleepiness (EDS) is mediated by loss of dopaminergic function by using dopaminergic specific single photon emission computed tomography (SPECT)…Density of metabotropic glutamate receptors subtype 1 in de novo patients with Parkinson’s disease using 11C-ITMM PET
Objective: To investigate the mapping of metabotropic glutamate receptor subtype 1 (mGluR1) in elderly normal and de novo patients with Parkinson's disease (PD) using N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-4-11C…