The assessment of quality of life in patients with early and moderately advanced Huntington disease
Objective: The aim of the study was to determine if available quality of life related scales are useful to detect the deterioration of quality of…Enroll-HD: A global clinical research platform for Huntington’s disease
Objective: To provide an update on the global observational registry study of Huntington's disease (HD) included in Enroll-HD, a platform for HD clinical research. Background:…Specific in-patient’s rehabilitation improves postural and gait instability in Huntington’s disease
Objective: To evaluate long-term effects of targeted rehabilitation on postural and gait stability in the early and middle stages of Huntington disease (HD). Background: HD…Clinical and neuroimaging correlations in early manifest Huntington’s disease patients: Default mode network properties according to resting-state functional MRI
Objective: (1) To compare pattern of spontaneous activity within default mode network (DMN) between early manifest Huntington's disease (HD) patients and healthy controls and (2)…Epidemiology and economic burden of falls and fractures in patients with Huntington’s disease
Objective: To assess epidemiology and economic burden of falls and fractures among Huntington's disease (HD) patients. Background: The clinical course of HD is characterized by…Interleaved pro- and anti-saccade performance in Huntington’s disease
Objective: To investigate suppression of automatic movements and execution of voluntary motor commands in an early stage Huntington's disease patients. Background: The ability to suppress…Predictors of quality of life in Huntington’s disease. A longitudinal observational study
Objective: To analyze predictors and progression of quality of life in patients with Huntington's disease (HD), on a longitudinal assessment over two years. Background: HD…Neurophysiological evidence of posterior-cortical alterations in premanifest Huntington’s: An event-related brain potentials study of face and face-like objects processing
Objective: To investigate the behavioral and neurophysiological correlates of face and face-like-object recognition in premanifest Huntington's disease (preHD). Background: PreHD provide an excellent framework to…Alternatives for reducing chorea in Huntington disease, a long-term trial (ARC-HD): Updated week 8 results for the switch cohort
Objective: To evaluate the sustained safety and efficacy following overnight switch from tetrabenazine (TBZ) to deutetrabenazine in patients with chorea associated with Huntington disease (HD).…Evaluation of quality of life (QOL), patient- and clinician-reported outcomes with deutetrabenazine treatment of chorea in Huntington disease in first-HD
Objective: To assess if deutetrabenazine treatment of chorea associated with HD resulted in changes in QoL, Patient Global Impression of Change (PGIC), or Clinical Global…