Altered glutamate response and calcium dynamics in iPSC derived striatal neurons from XDP-patients
Objective: Our objective was to generate an in vitro model of XDP based on striatal neurons differentiated from induced pluripotent stem cells (iPSC), followed by…Relative hypoglycemia induces acute chorea followed by chronic parkinsonism in a diabetic patient on hemodialysis: A case with sequential clinico-radiological correlate
Objective: To present a sequential clinico-radiological study of a diabetic patient on hemodialysis who developed acute chorea followed by chronic parkinsonism. Background: Hyperglycemic chorea is…Induced pluripotent stem cell-derived cortical neurons as a disease model for X-linked dystonia-parkinsonism
Objective: To elucidate the disease-associated cellular phenotype of induced pluripotent stem cell (iPSC)-derived cortical neurons of patients affected by X-linked dystonia-parkinsonism (XDP). Background: XDP is…Phosphorylation by GSK-3β enhances binding of metal ion induced tau oligomers to neutral lipid surfaces
Objective: To dissect the complex interplay of tau hyperphosphorylation, metal ion induced oligomer formation and membrane interactions applying single particle fluorescence techniques. Background: Fibrillar deposits…Propranolol therapy for tardive dyskinesia: A retrospective examination
Objective: To examine the tolerability and effectiveness of propranolol in treating tardive dyskinesia (TD). Background: TD is a disabling, often irreversible, movement disorder that results…1 to 40 years later: Delayed effects of brain radiation presenting as parkinsonism
Objective: To report 3 adult cases of delayed radiation induced parkinsonism, with latency ranging from 1 to 40 years. . Background: Unequivocal radiation induced parkinsonism…Age associated effects of levodopa administration on striatal acetylcholinesterase activity
Objective: The aim of this study was to compare short- and long-term effects of levodopa on acetylcholinesterase activity in young and old rat brain striatum.…Manganese-induced parkinsonism and motor neuron damage- Can there be a relationship?
Objective: The aim of the study was evaluation of clinical, radiological and ENMG characteristic of ephedronic encephalopathy(EE). Background: The ephedrone abuse is widely spread among…Chorea – Ballism drug induced in replacement treatment with thyroid hormones – Case presentation
Objective: We present the case of a 56 years-old female patient that presented chorea movements after the initiation of replacement treatment with thyroid hormones. Background:…A comparative study of clinical profile of patients of drug induced parkinsonism with idiopathic Parkinson’s disease
Objective: Drug induced parkinsonism (DIP), caused by various group of drugs, is second most common etiology of parkinsonism after Idiopathic Parkinson's disease (IPD). No major…