Identifying freezing of gait and falls in Parkinson’s disease patients using a body-worn sensor
Objective: The aim of the present study is to objectively detect and quantify freezing of gait (FOG) and falls in Parkinson's disease (PD) patients during…Gait impairment is more than a motor symptom in Parkinson’s disease
Objective: To examine the relationship of gait impairment of Parkinson's disease (PD) patients with different clinical factors including motor function, non-motor function and cognitive function.…Selenotranscriptomic analyses identify signature selenoproteins in brain regions in a mouse model of Parkinson’s disease
Objective: In this study, we investigated the selenotranscriptome (24 selenoproteins in total) in five brain regions (cerebellum, substantia nigra, cortex, pons and hippocampus) in a…Quantifying daily living transitions in patients with Parkinson’s disease using a body-fixed sensor
Objective: To test whether measures of everyday sit-to-walk and walk-to-sit differ between patients with Parkinson's disease (PD) and healthy older adults (HOA) and between mild…Localization and functional study of synaptic vesicle protein synaptogyrin-3 (SYNGR3) on dopaminergic neuronal system
Objective: To investigate (1) the intracellular localization of SYNGR3 and its interaction with dopamine transporter (DAT); (2) how expression of SYNGR3 in neurons affects dopamine…A whole brain anatomical network model and its application in PD research
Objective: To build a frame of whole brain anatomical network for incorporating different data from different studies with different brain parcellations and resolutions, to evaluate…Bi-hemispheric phase synchronization in patients with Parkinson’s disease during stance, gait and upper limb motor tasks
Objective: To begin exploring if and how bi-hemispheric cortical phase synchronization (PS), as reflected by electroencephalography (EEG), during free overground walking, is associated with gait…Effect of intra-striatal 6-OHDA lesion on extra-striatal structures in the mouse
Objective: Characterization of extra-striatal manifestations in the 6-hydroxydopamine (6-OHDA) Parkinson's disease (PD) animal model. Background: PD is a neurodegenerative disorder characterized by progressive loss of…Increased energy expenditure in early Parkinson’s disease during exercise
Objective: To measure both resting energy expenditure rate (REER) and energy expenditure during mild to moderate exercise in patients with early Parkinson's disease (PD) that…Hyperin inhibits lipopolysaccharide-induced microglia activation through p38 and NFκB signaling
Objective: In this study, we aimed to investigate hyperin's potentiality in inhibition of neuroinflammation. Background: Hyperin is an active compound isolated from Rhododendron brachycarpum G.…