Selegiline drives autophagic secretion of α-synuclein
Objective: Our aim is to elucidate how selegiline drives extracellular secretion of α-synuclein (αS) and whether selegiline-induced αS secretion affects cell-to-cell transmission of αS. Background:…A network imaging biomarker of X-linked dystonia-parkinsonism
Objective: To characterize a metabolic brain network associated with X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP, DYT/PARK-TAF1, Lubag) is an X-linked recessive movement disorder characterized…Levodopa-entacapone-carbidopa-infusion treatment in Parkinson’s disease: A six-month follow-up study
Objective: Objectives of this study were to evaluate changes in medication, adverse events and early discontinuations of levodopa-entacapone-carbidopa-intestinal-gel (LECIG) treatment in advanced Parkinson’s disease (PD).…Digital mobility sub-study in the Parkinson’s Progressive Marker Initiative (PPMI) study.
Objective: To test the feasibility and validity of digital mobility data for enrichment of the prodromal screening and to assess the sensitivity of these measures…Identifying delirium in Parkinson’s: evaluation of existing tools and measures
Objective: To evaluate the diagnostic accuracy of tools to identify delirium in inpatients with Parkinson’s disease (PD). Background: Delirium is a serious acute state of…Impact of the severity of Parkinson’s disease on skin elasticity
Objective: To investigate changes in skin elasticity according to the severity of symptoms of Parkinson's disease. Background: Parkinson's disease (PD) is a neurodegenerative disease caused…Istradefylline effect on Parkinson’s Disease Tremor, Motor symptoms and non-Motor symptoms.
Objective: Istradefylline is FDA approved for use in patients with PD treated with carbidopa-levodopa to reduce off time. GUH Movement Disorder Group has observed that…A rare case of PDE10A associated dystonia with bilateral striatal lesions
Objective: To describe an interesting and rare case of cervical dystonia associated with PDE10A mutation. Background: Dystonia is the third most prevalent movement disorder in…Impulse Control Disorder and medication management in Patients with Early-Onset Parkinson’s Disease
Objective: To assess the usage frequency of dopamine agonists (DA), the prevalence of impulse control disorder (ICD) in patients with Early-onset Parkinson’s Disease (EOPD), and…Ethnic and Gender Disparities in Access to Deep Brain Stimulation for Parkinson’s Disease Among Participants in C-OPN
Objective: To study the disparities in gender and ethnicity and the related contributing factors in Parkinson’s disease (PD) patients who require deep brain stimulation (DBS),…
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