Progression of milestones by clinical types in progressive supranuclear palsy: a longitudinal observational study of a cohort of patients with PSP/CBD (the JALPAC project)
Objective: To elucidate the natural history of the PSP clinical phenotype Background: Recently, various clinical types of PSP have been reported, but details on their…Impulse control disorders in Parkinson’s disease; description of a New Zealand cohort
Objective: Impulse control disorders (ICDS) are a recognised complication of dopaminergic therapy for Parkinson’s disease. We wanted to assess the rates of ICDs in New…Brain metabolic patterns in progressive supranuclear palsy phenotypes
Objective: To describe changes in cerebral glucose metabolism in patients with different described clinical phenotypes of PSP and to correlate them with the clinical manifestations of the disease. Background:…Mutational analysis of COQ2 in Chinese patients with multiple-system atrophy
Objective: To investigate the involvement of COQ2 variants in Chinese sporadic cases with multiple-system atrophy. Background: Multiple-system atrophy (MSA) is a rapidly progressive neurodegenerative disease…Gait and Cognition in Progressive Supranuclear Palsy: A Significant Association
Objective: In this study we explored the association between gait parameters and cognitive function of PSP. Background: Gait and cognition are interrelated in patients with…Utility of THK-5351 tau-PET for differential diagnosis in patients with hypokinetic-rigid syndromes.
Objective: The objective of our study is to investigate the use of THK-5351 tau- PET-imaging as an additional tool for differential diagnosis in hypokinetic-rigid syndromes suggestive…Gait characteristics in Atypical Parkinsonism
Objective: We investigated gait characteristics of progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), with the aim to elucidate relatively specific disease differences in…Freezing of gait is an early clinical feature of progressive supranuclear palsy
Objective: We attempted to identify any sign or symptom to diagnose progressive supranuclear palsy (PSP) earlier. Background: Early clinical diagnosis of progressive supranuclear palsy PSP…Gut Microbiota in Multiple System Atrophy
Objective: To investigate the gut microbiome and metabolome in MSA Background: Experimental models of prion-like cell-to-cell transfer of alpha-synuclein(AS) and its ability to spread from the…Do median-nerve evoked blink reflexes allow early differentiation between PD and PSP in patients with debuting parkinsonism?
Objective: Do median-nerve elicited blink reflex responses enable early differentiation between PD and PSP in patients with idiopathic parkinsonism? Background: Differentiation between PD and PSP in…