Efficacy of Tozadenant in Animal Models of Non-Motor Symptoms of Parkinson’s Disease
Objective: Investigate the potential of tozadenant (TOZ) to alleviate the non-motor symptoms of Parkinson's disease using multiple animal models. Background: TOZ is an oral, selective…The Relationship between Olfactory Function and Clinical Subtypes of Parkinson’s Disease
Objective: The aim of this study was to investigate the relationship between the degree of olfactory function and motor subtype of Parkinson's disease (PD). Background:…Olfactory dysfunction in patient of Scans Without Evidence of Dopaminergic Deficit with parkinsonian bradykinesia
Objective: To investigate the differences of olfactory dysfunction in patients within SWEDDs Background: The concept of SWEDD(scans without evidence of dopaminergic deficit) originates from the clinical…Effect of Urinary Dysfunction on Depression and Anxiety Development in Parkinson’s Disease
Objective: To investigate the relationship between urinary dysfunction (UD) and anxiety and depression in Parkinson's Disease (PD). Background: Urinary dysfunction is one of the…The Non-Motor Symptoms Questionnaire and Non-Motor Symptoms Scale for use in Sweden
Objective: To translate the Non-Motor Symptoms Questionnaire (NMSQ) and the Non-Motor Symptoms Scale (NMSS) into Swedish, and test their linguistic validity and user-friendliness. Background: Non-motor…Speech and voice response to levodopa in late-stage Parkinson’s Disease patients: report from an acute levodopa challenge
Objective: to assess the change of speech and voice after an acute L-dopa challenge in late-stage Parkinson’s disease (LSPD). Background: PD patients are classically affected…Subjective visual vertical in patients with early Parkinson’s disease
Objective: To identify the changes of subjective visual vertical and any correlation between SVV and cognitive/motoric dysfunctions in Parkinson's disease. Background: Dysfunction of sensory system is…Impulsive-compulsive behaviors in patients with Parkinson´s disease in Kannur, India
Objective: The main aim of the project was to determine the frequency of impulsive compulsive behaviors (ICB) in patients with Parkinson´s disease (PD) in Kannur,…Differential effects of ventral or dorsal predominant dopaminerjic denervation of striatum on development of dopamine dysregulation syndrome and punding in a rat model of parkinsonism
Objective: To model and assess the differential effects of ventral or dorsal predominant dopaminergic denervation of striatum on development of impulsive compulsive behaviors (ICB) in…Non-motor features of p.A53T α-synuclein mutation carriers compared to sporadic Parkinson’s disease in a PPMI cohort .
Objective: To evaluate the prevalence of non-motor symptoms in p.A53T SNCA-related PD patients as compared to sporadic PD (sPD) patients. Background: p.A53T α-synuclein (SNCA) mutation…