Rapid cognitive decline and new-onset psychosis after GPi DBS in a severe GBA mutation carrier: a case demonstrating the importance of genetic screening pre-DBS
Objective: To report the impact of globus pallidus internus (GPi) Deep Brain Stimulation (DBS) on cognition and neuropsychiatric symptoms in a severe glucocerebrosidase (GBA1) mutation…Tremor characteristics differentially respond to levodopa and subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: To identify factors predictive of responsiveness of tremor to levodopa and STN-DBS. Background: Tremor in Parkinson’s disease (PD) is phenotypically variable and has an…Olfactory sniffing is altered in patients with Parkinson’s disease
Objective: To develop an objective non-verbal non-task-dependent olfactory test for PD detection. Background: Olfactory decline may precede motor symptoms by several years or decades in…monogenic parkinson´s disease in a chilean cohort
Objective: To describe the minimum prevalence and distribution of monogenic forms of PD in a chilean cohort Background: About 3–5% of Parkinson’s disease (PD) patients…The effect of botulinum toxin on anxiety in cervical dystonia.
Objective: To assess the impact of botulinum toxin injections (BoNT) on anxiety symptoms and motor symptoms in cervical dystonia (CD) during one treatment cycle. Background:…An Open-Access Model for Parkinson’s Disease Progression
Objective: To model the progression of PD by developing a hidden Markov model which incorporates nonlinear effects of disease severity and medication on clinical scores.…Effect of levodopa on the interpretation of social interactions in people living with Parkinson’s disease
Objective: Better understand the social interactions by assessing the effect of oral levodopa on the social cognition abilities in fluctuating PD patients without significant cognitive disorder.…Theoretical Definition of DBS Electrode Misplacement
Objective: To propose a definition of Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) electrode misplacement (MP) based on ideal brain connectivity strength. Background: MP is defined…Can very early levodopa prevent self-injury in Lesch-Nyhan Disease?
Objective: To determine whether levodopa treatment starting at a very young age can prevent the development of the full clinical phenotype in Lesch-Nyhan disease. Background:…Genome Wide Association Studies using TRACTOR reveals new associated loci with Parkinson Disease in a Latino Cohort
Objective: Our objective was using TRACTOR[1], which performs Genome Wide Association Study (GWAS) including Local Ancestry (LA) information, in Parkinson Disease (PD) using data from…
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