Investigating glutamate toxicity associated to Park2 mutations in pre-clinical models of Parkinson’s Disease
Objective: To generate and characterize induced pluripotent stem cells (iPSCs)-derived in vitro cellular models of Autosomal Recessive Juvenile Parkinsonism (ARJP) carrying Park2 mutations with a…The effect of botulinum toxin on anxiety in cervical dystonia.
Objective: To assess the impact of botulinum toxin injections (BoNT) on anxiety symptoms and motor symptoms in cervical dystonia (CD) during one treatment cycle. Background:…Anodal transcranial direct current stimulation could change the metabolomic profiles of cerebrospinal fluid in Parkinson’s disease
Objective: We tried to identify meaningful metabolite change after anodal tDCS in clinically diagnosed PD patients by adopting metabolomic analysis Background: Transcranial direct current stimulation…Jaw opening myoclonus in Subacute Sclerosing Panencephalitis: A new phenotypic observation which may be a diagnostic clue
Objective: We aimed to study the frequency of jaw myoclonus in subacute sclerosing panencephalitis (SSPE). Background: SSPE is a rare disorder due to mutant measles…Alzheimer’s Disease Co-pathology and its Influence on Biofluid Biomarkers in Autopsied Subjects from the PPMI Study
Objective: To examine the relationship between biofluid biomarkers and post-mortem pathological findings in autopsied subjects from the Parkinson’s Progression Marker Initiative (PPMI). Background: The PPMI…Association of vestibular disorders with autonomic dysfunction in Parkinson’s Disease
Objective: Investigation of changes in VOR and VCR parameters in PDpatients in relation to motor and autonomic disorders severity. Background: Vestibulo-ocular reflex (VOR) and vestibular-colic…Sex-specific speech correlates of dysphagia in Parkinson’s disease
Objective: To identify speech characteristics that directly correlate with dysphagia in advanced Parkinson's disease (PD) patients, using both acoustic and perceptual analyses of speech, with…Multicenter, randomized, placebo-controlled, double-blind, parallel-group proof-of-concept study of lixisenatide in patients with early Parkinson’s disease (PD): the LIXIPARK trial (NCT03439943)
Objective: To evaluate the “disease-modifying” effect of lixisenatide as adjunct to antiparkinsonian medications in patients with early PD. Background: Lixisenatide, a glucagon-like peptide 1 receptor…Oh man: Why are males more prone to Musician’s Dystonia?
Objective: Our objective was to evaluate gender differences of risk factors contributing to the development of Musician’s Dystonia. Background: Musician’s Dystonia (MD) is a task…Cardiovascular complications in Parkinsonism: insights from Luxembourg Parkinson’s Study
Objective: Our study aimed at determining the frequency and risk of cardiovascular diseases (CVDs) in Parkinsonian patients in the Luxembourg Parkinson’s Study (LuxPARK). Background: The…
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