Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synuclenopathies
Objective: We have investigated whether deposits of phosphorylated α-synuclein might be present in pancreatic tissue of subjects with synucleinopathies. Background: Parkinson’s disease patients experience a…Long-term efficacy and safety of incobotulinumtoxinA treatment for sialorrhea in Parkinson’s disease and other neurologic conditions
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with a 48-week extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 U or…Visual deficits of self-motion perception in Parkinson’s disease
Objective: To investigate unisensory and multisensory self-motion perception mediated by the visual and vestibular systems in PD. Background: Parkinson's disease (PD) is classically characterized by…Single-centre open label exploratory phase IIb pilot study of exogenous oral Melatonin for the treatment of Nocturia in adults with Parkinson’s disease
Objective: To evaluate the effect of melatonin on nocturia. Background: Nocturia is one of the commonest non motor symptoms in Parkinsons’ disease (PD), and has…Impact of injection guidance techniques on the efficacy and safety of incobotulinumtoxinA for sialorrhea
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with an extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U…Vowel characteristics associated with Parkinson’s disease in Cantonese
Objective: Dopaminergic treatment has been reported to help motor problem associated with Parkinson's disease (PD), but not speech motor. The current study examined vowel articulation…Non motor symptoms in parkinsonism: A cross sectional study
Objective: Non motor symptoms (NMS) in idiopathic Parkinson’s disease (PD) are well studied and has an effect on quality of life in PD. NMS in…Restless legs syndrome in Parkinson’s disease patients: a comparative study on prevalence, clinical features, motor and non-motor symptoms
Objective: We investigate the prevalence of restless legs syndrome in Parkinson’s disease patients and to identify associated clinical features, motor and non-motor symptoms. Background: Restless…Nursing diagnoses, outcomes and ICNP® interventions related to urinary dysfunction in Parkinson’s disease
Objective: To describe the nursing diagnoses, outcomes and interventions related to urinary dysfunction in Parkinson disease. Background: The complexity of motor and nonmotor symptoms in…Gut microbiota geography in Parkinson’s disease in the world
Objective: The 16 rRNA analysis and the shotgun metagenome analysis in our cohort were compared with 5 previous reports by others. Background: In PD patients,…