Striatal dopamine transporter availability changes reflect gastrointestinal dysautonomia severity in early Parkinson’s disease
Objective: To test the hypothesis that constipation and gastrointestinal (GI) dysautonomia may be correlated with nigrostriatal dopaminergic (DA) dysfunction in PD. Background: Constipation is a…Early gastrointestinal dysfunction is predictive of faster progression in Parkinson’s disease
Objective: To evaluate whether constipation at time of diagnosis has prognostic significance in terms of motor and cognitive progression in PD. Background: There is evidence…Pain is correlated with other motor and non-motor symptom in Parkinson’s disease
Objective: Study pain occurrence and appearance in Parkinson’s disease (PD), and its relationship with other motor and non-motor symptoms like constipation and footsteps. Background: The…Clinical characteristics of frailty in Parkinson’s disease
Objective: To assess the prevalence of frailty and its association with disease features in patients with Parkinson´s disease (PD). Background: Frailty is a multifactorial syndrome…Impulse control disorders and compulsive behaviours in Parkinson’s disease. Results from the COPPADIS Study Cohort
Objective: Our objective was to analyze the existence of impulse control disorders (ICDs) and compulsive behaviours (CBs) in Parkinson’s disease (PD) patients compared to control…Early stage Parkinson’s disease phenotypes
Objective: Identify Parkinson’s disease (PD) subpopulation clusters present at disease onset using a number of motor and non-motor phenotypes. Background: PD is considered a syndrome,…The Effect of Sleep Deprivation on Short-Term Memory and Emotion of Rotenone Treated Zebrafish Model of Parkinson Disease
Objective: We investigated the long-term consequences of sleep deprivation on short-term memory and emotion using a rotenone treated zebrafish model of Parkinson disease. Background: Parkinson…Subthalamic nucleus stimulation normalises effort-based decision-making in Parkinson’s disease
Objective: To compare the influence of levodopa and subthalamic nucleus stimulation (STN-DBS) on effort-based decision-making in Parkinson’s disease (PD). Background: Idiopathic PD is a neurodegenerative…Autonomic Dysfunction in Parkinson’s Disease: Role of New Surrogate Markers
Objective: The physiology of respiration is modulated by autonomic efferent neurons and circulating hormones. A continuous ambulatory monitoring of various respiratory parameters helps in early…“Frequency of autonomic and cardiovascular abnormalities in Mexican patients with early Parkinson’s disease”
Objective: To determine the frequency of dysautomic disorders and structural cardiac abnormalities in patients with early PD. Background: Parkinson´s disease (PD) is a neurodegenerative disease…