Distinct effects of apathy and dopamine on effort-based decision making in Parkinson’s disease
Objective: To determine if disrupted effort-based decision making (EBDM) underlies the syndrome of apathy in PD, and whether this disruption is modulated by the dopaminergic…α-synuclein propagation via olfactory pathway in non-human primate model
Objective: Recent studies have revealed that intracerebral injection of synthetic α-synuclein (α-syn) fibrils into olfactory bulb (OB) of mice induced prion-like propagation of α-syn aggregates…Skin Deposition of Pathological Alpha-Synuclein in Idiopathic REM-sleep Behavior Disorder and Parkinsonism
Objective: To assess cutaneous pathological Alpha-syn deposition in patients with iRBD, PD, atypical parkinsonism and controls. Background: Peripheral autonomic neurodegeneration may occur in early stages…Association between sleep duration and subsequent risk of Parkinson´s disease and survival: Data from NEDICES study
Objective: To evaluate whether sleep duration (i) is associated with a subsequent risk of Parkinson’ disease (PD); (ii) affects mortality rates in PD patients, using…Asymmetric olfactory deficit in H&Y stage-1 early onset Parkinson’s disease
Objective: To determine if the olfactory deficit in the early-stage Parkinson’s disease (PD) is asymmetric between the two hemispheres ipsilateral and contralateral to the onset…Clinical subtypes of Parkinson’s disease based on nonmotor symptoms: A cluster analysis
Objective: To classify patients with early Parkinson's disease based on nonmotor symptoms using a data-driven approach. Background: Heterogeneity of Parkinson’s disease provides the basis for…Altered amplitude of low-frequency fluctuations and functional connectivity in excessive daytime sleepiness in Parkinson disease
Objective: The present study aimed to explore the neural mechanism of Excessive daytime sleepiness (EDS) in Parkinson disease (PD). Background: EDS is common in PD,…Study of prevalence of non-motor symptoms in typical and atypical parkinsonism as compared to age and sex matched healthy controls
Objective: 1) To study prevalence and clinical characteristics of non-motor symptoms (NMS) in idiopathic parkinson disease (IPD) and atypical Parkinsonism (APD) as compared to age…Evaluation of the Effect of STN-DBS on the Gastrointestinal Symptoms in Patients with Parkinson’s Disease via GIQLI
Objective: Our aim is to evaluate the effects of Subthalamic Nucleus (STN)-DBS on the quality of life in PD patients by using the Gastrointestinal Quality…The Prevalence of Gastrointestinal Symptoms in Parkinson’s Disease Patients in Bethesda Hospital, Yogyakarta, Indonesia
Objective: We were conducting the research to determine the prevalence of the gastrointestinal symptoms in Parkinson's disease patients in Bethesda Hospital, Yogyakarta, Indonesia, by using…