Total CSF alpha-synuclein is inversely associated with non-motor symptoms in a population of patients with Parkinson’s Disease
Objective: To evaluate the association between PD non-motor symptoms (NMS) and CSF levels of neurodegeneration-related proteins in a population of PD patients, aimed at identifying…Effect of CDNF on non-motor symptoms like motivation, fear, stress and depression-like behavior
Objective: The goal of this study was to characterize the effect of CDNF on motivation, stress and depression-like behavior, because most of the non-motor symptoms,…Non-Motor Symptom In Young Onset Parkinson Disease as a Cause of Pharmacoresistence In Epilepsy
Objective: To report an interesting initial presentation of PD causing refractory epilepsy. Background: A lady with refractory depression, presented with first seizure at age 42,…Predictors and biomarkers of pain in newly diagnosed Parkinson’s disease patients during a two-year follow-up
Objective: To identify clinical characteristics, predictors and biomarkers of pain at baseline and after a two-year follow-up period in newly diagnosed drug-naïve Parkinson's Disease (PD)…The Gut Microbiota in a Canadian Parkinson’s Disease Cohort
Objective: To compare the gut microbiota between PD patients and matched controls in a Canadian cohort and to examine correlations between microbes and disease parameters…Temporal evolution of biomarkers from healthy ageing, isolated REM sleep behavior to early Parkinson’s disease
Objective: To study the temporal evolution of biomarkers of various modalities in healthy ageing controls (HC), the prodromal condition of isolated REM sleep behavior disorder…Traditional Chinese Medicine in treating for salivation and nocturia for patient with Parkinson’s disease
Objective: To explore the efficacy of one TCM formula, Lian-Se granule (LSG), in treating for salivation and nocturia for patient with Parkinson's disease (PD). Background:…Clinical evaluation of insomnia in Parkinson’s disease and its effect on the quality of life of patients
Objective: Assessment of the incidence of insomnia, its association with motor, neuropsychiatric disorders, clarifying the impact on the quality of life of patients with PD…Listen to the heart: Do loud vagal rhythms disharmonize the autonomic symphony in Parkinson’s disease patients with the LRRK2 mutation?
Objective: Assessment of cardiac autonomic function through standard and novel features of heart rate variability (HRV) in individuals who carry the G2019S mutation in the…Characterization of the gastrointestinal dysfunction in mice overexpressing the human mutation (A53T) of alpha-synuclein
Objective: The aim of this study was to determine if mice overexpressing the human mutation of alpha-synuclein develop gastrointestinal (GI) dysfunction, and to understand the…