Distinguishing ON from OFF Motor State by Phone Attribute Codes in Patients with Parkinson’s Disease
Objective: To detect differences of speech in patients with PD due to a variant motor state, i.e. ON and OFF. Background: Speech is a highly…Abnormal NMDA-related Electrophysiology in Parkinson Disease Dementia
Objective: Investigate mismatch negativity in Parkinson disease with dementia. Background: Parkinson’s disease with dementia (PDD) is an important cause of cognitive impairment in Parkinson’s disease…Hypometabolism of the posterior parietal cortex in Parkinson’s disease with mild cognitive impairment predicts the conversion to dementia: 5-year longitudinal observations
Objective: To investigate the neuroimaging marker that predict the conversion of mild cognitive impairment (MCI) to dementia in Parkinson’s disease (PD) patients. Background: Patients with…Higher motor cortex connectivity with subthalamic stimulation than with levodopa: A resting state fMRI study in Parkinson’s disease
Objective: To perform a direct comparison between the effect of levodopa medication and deep brain stimulation of the subthalamic nucleus (STN DBS) on functional brain…Association of Olfaction dysfunction with Brain Microstructure in Prodromal Parkinson disease
Objective: Investigating the association between olfactory dysfunction and connectometry patterns in UPSIT-matched prodromal and PD patients. Background: Parkinson’s disease (PD) is a heterogeneous neurodegenerative disease…Long-term and dopamine dependent dynamics of subthalamic nucleus local field potentials in Parkinson’s disease
Objective: Using a new deep brain stimulation (DBS) pulse generator device that can record local field potentials (Activa PC+S, Medtronic Inc.), the current experiment investigated…A comprehensive digital biomarker active testing and passive monitoring suite for the remote and frequent assessment of motor symptom progression in Parkinson’s disease
Objective: We present the development and design of a comprehensive digital biomarker smartphone application (app) for remote and frequent assessments of motor symptom severity and…Neuroinflammation Predicts Dompaminergic Deficit in Early Parkinson Disease: DAT SPECT Imaging Study
Objective: We aimed to investigate whether striatal Dopamine transporter (DaT) uptake could be predicted by Neutrophil to lymphocyte ratio (NLR) or measures of disease severity…The usefulness of 18 F-DOPA PET scan in diagnostically challenging patients at a movement disorder clinic
Objective: The aim of this study was to determine the usefulness of 18 F-DOPA PET scan in diagnostically challenging patients at our movement disorder clinic…Identifying the neural correlates of doorway freezing in Parkinson’s disease
Objective: We aimed to combine a previously validated virtual reality gait paradigm with functional Magnetic Resonance Imaging (fMRI) to investigate the neural correlates underlying doorway-provoked…