Olfactory dysfunction, sleep disturbances, neuronal loss, and regional brain atrophy in an inducible mouse model of Alpha-Synucleinopathy
Objective: The objective of this work is to develop a unique mouse model of spreading α-synucleinopathy to accelerate the development of novel disease-modifying treatments for…Altered connectivity in ventral and dorsal attentional networks in patients with Parkinson’s disease: Association with freezing of gait
Objective: To examine the changes in connectivity of the attentional networks in Parkinson's disease (PD) and their role in freezing of gait (FOG). Background: Deficits…Bupropion causing misdiagnosis in brain dopamine transporter imaging for parkinsonism
Objective: To report long-lasting effects of bupropion on brain dopamine transporter (DAT) binding in a patient with depression and parkinsonism. Background: Striatal DAT imaging is…Association between peripheral inflammation and DATSCAN data of the striatal nuclei in different motor subtypes of Parkinson Disease
Objective: This work was designed to investigate peripheral inflammation in terms of Neutrophil-Lymphocyte ratio (NLR) concerning loss of dopaminergic uptake in caudate and putamen on…Clinical and functional network features of visuoperceptual disturbances in Parkinson’s disease
Objective: To clarify the relationship between functional connectivity changes in the brain and visuoperceptual disturbances in patients with Parkinson's disease (PD). Background: Patients with PD…Compensatory functional activations in early-stage Parkinson’s disease: a cross-sectional motor planning fMRI study
Objective: To assess the dynamic brain responses during planning motor fMRI task in an early-stage cohort of Parkinson’s disease patients. Background: Parkinson’s disease (PD) is…Transcranial imaging of substantia nigra hyperechogenicity in a Chinese cohort of Parkinson’s disease
Objective: In this research we set out to study the diagnostic value of TCS in Parkinson's disease. Background: An increased echogenicity of the substantia nigra…The use of DaT-SPECT scanning in the differential diagnosis of Parkinsonism: Are guidelines being followed?
Objective: The aim of this study was to assess the adherence of a UK National Health Service (NHS) Parkinson’s disease service to National Institute for…Closed loop spinal cord stimulation restores locomotion and desynchronizes corticostriatal beta oscillations
Objective: To test if closed loop Spinal Cord Stimulation (SCS) could be used to restore locomotion in a 6-hydroxydopamine (6-OHDA ) rodent model of Parkinson's…Parkinson’s disease motor symptoms are linked to red nucleus volume and cerebellar metabolism
Objective: To investigate the involvement of the red nucleus (RN) and cerebellum in the motor symptoms of Parkinson's disease (PD). Background: Numerous studies have shown…