Longitudinal changes in Neuromelanin MRI Signal in Parkinson’s Disease
Objective: To examine the longitudinal changes in neuromelanin (NM) MRI signal in the substantia nigra (SN) in Parkinson’s disease (PD). Background: PD is characterized by…Effects of N-methyl-D-aspartate receptor antagonist in Parkinson’s disease with dementia
Objective: We conducted this longitudinal study to confirm the efficacy of memantine for PDD by analyzing comparative changes in regional cerebral blood flow (rCBF) and…White Matter Hyperintensities and Mortality among Patients with Parkinsonism in Olmsted County, MN (1995-2010)
Objective: To examine white matter hyperintensity grade (WMHG) by parkinsonism type, and the association between WMHG and mortality among incident parkinsonism patients in a population-based…EEG microstates changes in response to increase in dopaminergic stimulation in treated typical Parkinson’s disease patients without clinical fluctuations
Objective: Neurotropic drugs may modulate Electroencephalography (EEG) microstates (MS), but there are no works showing EEG MS default-mode network changes in response to dopaminergic stimulation…Cerebellar atrophy in different motor and non-motor subtypes of Parkinson’s disease
Objective: The cerebellum is involved in Parkinson’s disease (PD). This study was to investigate, using MRI and voxel-based morphometry (VBM), morphometric changes of cerebellum in…Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait
Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…Substantia Nigra Echogenicity Associated with Clinical Subtypes of Parkinson’s Disease
Objective: We classified Parkinson’s disease (PD) patients into different subtypes and evaluated the correlation between the substantia nigra (SN) echogenicity and disease progression. Background: It…Automated Differential Diagnosis of Parkinsonian Syndromes Using FDG-PET Metabolic Brain Network Analysis
Objective: To discriminate among parkinsonian patients using an automated network analysis of FDG-PET brain images. Background: Clinical differentiating among parkinsonian syndromes: Parkinson’s disease (PD), multiple…DAT-imaging and clinical phenotypes of Parkinson’s disease
Objective: To evaluate the relationship of motor and nonmotor symptoms with striatal dopaminergic denervation in a cohort of symptomatic PD patients with positive DAT-imaging Background:…α4β2-nicotinic receptor availability in Parkinson’s disease MCI and healthy controls: A pilot imaging study using [18F]-XTRA PET
Objective: We aimed to show that a radiotracer with high affinity to cortical and hippocampal α4β2-nicotinic cholinergic receptors (1) would be reduced in regions associated…