Compliance with national and international guidelines in the treatment of non-motor symptoms in late stage Parkinson’s disease
Objective: Against a background of the national and international Parkinson's disease (PD) treatment guidelines, the aim of this study was to investigate to which degree…Marked reduction of energy supply due to levodopa treatment in patients with Parkinson’s disease and healthy controls
Objective: To investigate the influence of a standardized, placebo-controlled administration of levodopa on cerebral bioenergetics in patients with Parkinson’s disease (PwPD) and healthy controls (HCs).…The Role of Adaptive Immunity caused by α-synuclein Recognition Specific Sequence Peptide on the Onset of Parkinson’s Disease Pathogenesis
Objective: We investigated whether α-synuclein-derived peptides (recognized specific sequence in α-synuclein) can drive T-cell response and evaluated the neurotoxicity of α-synuclein peptide-specific T-cell in Parkinson’s…Real-World Utilization of Istradefylline Among Patients with Parkinson’s Disease
Objective: This study examined real-world utilization of istradefylline and other PD-related medications before and after istradefylline initiation. Background: Istradefylline is indicated as adjunctive therapy to…Rehabilitation robot-assisted gait training for Parkinson’s disease: A systematic review and meta-analysis of its effects on lower extremity dyskinesia and motor function
Objective: This systematic review and meta-analysis aimed to evaluate the efficacy of RAGT in improving lower extremity dyskinesia and motor function-related indicators, including the 10-meter…Hemiparkinsonism secondary to a cerebral cavernous malformation (CCM)
Objective: To describe a case of secondary parkinsonism of unhabitual cause and complex treatment. Background: Secondary parkinsonism constitutes approximately 15% of all parkinsonism cases in…Quercetin hinders Glial Activation to Alleviate the Cadmium Induced Dopaminergic Alteration via TNFα mediated CAMKIIα/ERK activation
Objective: The present study has therefore been carried out identify neuroprotective role of quercetin in alleviating the cadmium induced dopaminergic dysfunctions via glial mediated deactivation…The induction of mitochondrial damage by alpha synuclein In Parkinson’s disease.
Objective: Alpha synuclein aggregation have been indicted in the process of neuronal cell loss in Parkinson's disease; however, there have been several hypothesis to explain…Prevalence of multiple system atrophy in Europe: literature review
Objective: To provide a literature overview on the prevalence of multiple system atrophy (MSA) in selected European countries Background: Multiple system atrophy (MSA) is a…Case series of Steroid-responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT); different presentations and different treatment outcomes.
Objective: to describe the characters of 4 female patients suffering from SREAT, phenotypes of movement disorders, cognitive impairment, and outcomes. Background: Steroid-responsive encephalopathy associated with…
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