Postural deformities in Chinese patients with multiple system atrophy
Objective: The objective of our study was to investigate the frequency and clinical characteristics of the postural deformities in Chinese patients with multiple system atrophy…An atutopsy case of argyrophilic grain disease, clinically presenting with Parkinson dementia
Objective: We here reported argyrophilic grain disases (AGD) with clinical diagnosis of Parkinson dementia. Background: AGD is a four-repeat tauopathy and its accumulation (argyrophilic grain…Burden among Patients with Progressive Supranuclear Palsy
Objective: To quantify the economic costs and examine the most common co-morbidities of patients with progressive supranuclear palsy (PSP) in the United States. Background: PSP…Serum insulin-like growth factor-1 levels in parkinsonism or dementia disorders
Objective: To investigate serum insulin growth factor-1 (IGF-1) levels in neurodegenerative disease and to correlate clinical parameters. Background: IGF-1 is highly expressed in the central…Nilotinib for treating MSA: A preclinical proof of concept study
Objective: To assess the effects of nilotinib on motor behavior, α-synuclein burden and surrogate markers of neurodegeneration in a transgenic mouse model of multiple system…Accuracy of the International Parkinson Disease and Movement Disorder Society Progressive Supranuclear Palsy Diagnostic Criteria (IPD-MDS-PSP)
Objective: To evaluate the accuracy of the IPD-MDS-PSP criteria to differentiate PSP-Richardson (PSP-R) from PSP-parkinsonism (PSP-P), the most common PSP phenotypes. Background: The new International…Methylphenidate in Progressive Supranuclear Palsy [PSP] – Old drug, New Indications?
Objective: To evaluate whether Methylphenidate can improve some symptoms of PSP. Background: PSP is a neurodegenerative disorder with limited therapeutic options. Methylphenidate[MPH] , a drug…Vascular parkinsonism: Clinical features and comparison with Parkinson’s disease
Objective: To define the clinical features of vascular parkinsonism (VP) and compare it to idiopathic Parkinson’s disease (iPD). Background: The main differential diagnosis of VP…The Timed Up & Go test (time) is inversely associated with fall frequency in progressive supranuclear palsy
Objective: This study aimed to elucidate the appropriate assessments associated with fall frequency in progressive supranuclear palsy (PSP). Background: PSP is an adult-onset neurodegenerative disease,…Atypical Response to Apomorphine in a Patient with Multiple System Atrophy
Objective: Multiple system atrophy (MSA) is a sporadic neurodegenerative disease clinically characterized by cerebellar signs, parkinsonism and autonomic dysfunction. MSA is classified into two sub-types;…