The impact of APOε4 polymorphisms and mutations in the GBA gene on the clinical features of Dementia with Lewy Bodies among Ashkenazi Jews
Objective: We aimed to explore the frequency and clinical impact of APOε4 polymorphisms in a cohort of Ashkenazi Jewish (AJ) patients with Dementia with Lewy…Cerebellar signs in progressive supranuclear palsy
Objective: To present a patient with cerebellar ataxia and a pathologically confirmed diagnosis of PSP. Background: Progressive supranuclear palsy (PSP) is an atypical form of…Usefulness of combined examination using Frontal Assessment Battery (FAB) and Single Photon Emission Computer Tomography in the differentiation of 4 repeats (4R) tauopathic atypical parkinsonism
Objective: The aim of the work is to analyze whether combined examination of the frontal lobe using single photon emission computer tomography (SPECT) and Frontal…Apolipoprotein E and multiple system atrophy
Objective: This study evaluated genetic associations of Apolipoprotein E alleles with risk of multiple system atrophy (MSA) and α-synuclein pathology, and also examined whether apolipoprotein…Reversible Extrapyramidal features as unusual presentation of central pontine myelinolysis: A case report
Objective: To be acquainted with the extrapyramidal symptoms developed during the course of central pontine myelinolysis. To emphasize the importance of neuroimaging in the diagnosis…Clinical spectrum of vascular Parkinsonism: A hospital-based study in south India
Objective: to Study the profile of akinetic rigid syndromes with special reference to Vascular Parkinsonism Background: Parkinson disease (PD) is a primary neurodegenerative disease but…Serum fractalkine levels in Parkinson’s disease: Evidence for neuroinflammation
Objective: Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by loss of dopamine neurons in the substantia nigra. We measured neuroinflammatory marker fractalkine in…Atypical Dopamine Responsive Parkinsonism in HIV Seroconversion
Objective: To add to the current body of knowledge of the association of HIV infection and dopamine responsive parkinsonism. Background: South Africa has one of…Quantitative Midbrain Measurement in Diagnosing Variants of Progressive Supranuclear Palsy
Objective: To evaluate the effectiveness of quantitative midbrain measurements in differentiating vPSP from multiple system atrophy (MSA) and Parkinson’s disease (PD). Background: Newly published criteria…ARISE study: Study Design and Baseline Characteristics for a Phase 2 Trial of the Anti-Tau Antibody ABBV-8E12 in Progressive Supranuclear Palsy
Objective: This double-blind, placebo-controlled phase 2 study (M15-562 ARISE study, NCT02985879) assesses the safety and efficacy of ABBV-8E12 treatment in patients with progressive supranuclear palsy…