Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Use of stimview technology in deep brain stimulation of Parkinson´s disease patients
Objective: We present our experience of Stimview technology in the neurostimulation of 5 patients with Parkinson´s disease (PD). Background: It is common to make adjustments…The effect of APOE ε4 on striatal vesicular monoamine transporter-2 density in Parkinson’s disease
Objective: To evaluate the effect of apolipoprotein E 4 (APOE 4) on striatal vesicular monoamine transporter-2 (VMAT2) density in Parkinson’s disease (PD).To evaluate the effect…Effect of ADX-88178, a highly-selective mGlu4 PAM, on parkinsonism, dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset
Objective: To investigate the effect of the metabotropic glutamate 4 (mGlu4) positive allosteric modulator (PAM) ADX-88178 on parkinsonism, dyskinesia and psychosis-like behaviours (PLBs) in the…Argentine Translation and Adaptation of the Scale for the Assessment and Classification of Ataxia (SARA)
Objective: Translate and cross-culturally adapt this instrument into Spanish and to carry out a pilot test for its subsequent validation in this language. Background: Ataxias…Expression profile of circRNA in peripheral blood mononuclear cells of patients with Parkinson’s disease and atypical parkinsonian syndromes
Objective: This study aimed to uncover circRNAs subsets with diagnostic potential for APS and iPD. Background: Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP)…Cortical mean diffusivity and cortical thickness in essential tremor
Objective: To study the cortical microstructure in ET patients Background: Essential tremor (ET) is a common movement disorder, but the pathogenesis is poorly understood. Several…Case series of Steroid-responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT); different presentations and different treatment outcomes.
Objective: to describe the characters of 4 female patients suffering from SREAT, phenotypes of movement disorders, cognitive impairment, and outcomes. Background: Steroid-responsive encephalopathy associated with…18F-Florzolotau PET imaging of tau pathology in the living brain of patients with corticobasal syndrome
Objective: To analyze the topographical patterns of tau pathology in the living brains of patients with CBS using 18F-Florzolotau PET imaging and to examine whether…First Report of ERCC1-Associated Adult-Onset Hepatocellular Carcinoma, Ataxia, and Cognitive Decline
Objective: To delineate the clinical presentation, exam phenomenology, brain MRI findings and to review the literature of the first reported adult-onset case of ultrarare ERCC1…
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