Plasma biomarkers in iRBD patients serve as potential markers of early PD and motor severity
Objective: We aimed to investigate biomarkers of inflammation and neuroaxonal damage in people with isolated REM sleep behaviour disorder (iRBD) compared to controls, and understand…Trajectories of Physical Performance in Prodromal and Early Parkinson’s Disease
Objective: To describe trajectories of physical performance in prodromal and early Parkinson’s Disease (PD). Background: There is a need to better characterize the prodromal and…MR-morphological changes in PD patients with heterozygous GBA mutation
Objective: This study investigates possible cerebral morphological differences between GBA-gene-mutation carriers with Parkinson´s disease (PD) and PD-patients without GBA-gene-mutation depending on in- or exclusion of…Machine learning selects common fMRI features of cognitive impairment in Parkinson’s disease from cross-institution datasets
Objective: To obtain common features of Parkinson's disease (PD) with cognitive impairment (CI) in resting-state functional MRI (rs-fMRI) from cross-institution datasets by adopting machine learning.…Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Localisation of distinct brain networks in premanifest and manifest Huntington’s disease
Objective: To map the brain networks underlying Huntington’s Disease (HD), testing whether there are distinct networks involved in premanifest and manifest disease stages. Background: HD…Comparing the Connectivity of Thalamic Deep Brain Stimulation Sites in ET and ET Plus Syndrome
Objective: To examine differences in structural connectivity of deep brain stimulation (DBS) sites in patients with essential tremor (ET) and essential tremor plus syndrome (ET-plus).…Dyskinesia and adherence to safinamide and opicapone in fluctuating patients with Parkinson’s disease: observational retrospective study
Objective: To assess differences in the new onset or worsening of baseline dyskinesia after the introduction of safinamide (SA) or opicapone (OP) as add-on therapy…18F-Florzolotau PET imaging of tau pathology in the living brain of patients with corticobasal syndrome
Objective: To analyze the topographical patterns of tau pathology in the living brains of patients with CBS using 18F-Florzolotau PET imaging and to examine whether…Normative values for the Instrumented Timed Up and Go test in Parkinsonian populations
Objective: This study aims to define normative values for the Instrumented Timed Up and Go test using wearable inertial sensors in people affected by Parkinson’s…
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