Session Information
Date: Monday, June 20, 2016
Session Title: Quality of life/caregiver burden in movement disorders
Session Time: 12:30pm-2:00pm
Location: Exhibit Hall located in Hall B, Level 2
Objective: To determine the range of motor symptoms in PD patients on early stages and their the influence on quality of life and daily activities.
Background: Parkinson’s disease (PD) is one of the most frequent neurodegenerative diseases. Along with the classic motor symptoms, it starts with a wide spectrum of non-motor symptoms.
Methods: 80 patients with PD on the early stages were included (male: female = 29: 51). 27,6% of patients had 1-1,5 stage of modified H&Y scale, 40% – 2nd and 32,5% – 2,5 stage. The medium age was 59,7 ±7,7 years; the mean duration of the disease – 3,1±2,7. The mixed form of PD predominated overothers (62,5%). We used Hoehn and Yahr scale modified by Lindvall to assess PD severity (Hoehn M., Yahr M., 1967, O. Lindvall, 1989); to assess the severity of the main symptoms of Parkinson’s disease – UPDRS scale; assess affective disorders – Hamilton Rating Scale – (M. Hamilton, 1959, 1999); non-motor symptoms – scale non-motor symptoms PD NMS (Chaudhuri K. R. et al., 2004); to assess the quality of life – a PDQ-39 (Peto V. et al., 1995), to assess the activities of daily living – scale Schwab and England (Scwab J.A. & England A.C., 1969).
Results: The mean score of the UPDRS (II+III) 23,3±9,0 points. The mean rigidity – 1,4±0,5 points, hypokinesia – 1,7±0,5, tremor – 1,2±0,6, aheyrokinez – 1,3±0,5, bradilalia – 0,6±0,3, hypomimia – 1,1±0,6, retropulsion – 0,3±0,5. 33,75% of the patients were disabled, among them 22,5% with mixed form, 7,5% – with akinetiko-rigid, 3,75% – with tremor predominant. There was a positive correlation between the degree of movement disorders and affective disorders (r=0,000001, p<0,05), non-motor symptoms (r=0,0005, p<0,05), quality of life (r=0,000008, p<0,05), activities of daily living (r=0,000001, p<0,05).
Conclusions: Even on the early stages of PD quality of life and daily activities are decreased, causing disability in some cases.
To cite this abstract in AMA style:
E.N. Gubanova, N.V. Fedorova. Motor symptoms in patients with early stages of Parkinson’s disease [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/motor-symptoms-in-patients-with-early-stages-of-parkinsons-disease/. Accessed May 9, 2025.« Back to 2016 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/motor-symptoms-in-patients-with-early-stages-of-parkinsons-disease/