Objective: To assess changes in the gait, balance and QOL in PD patients subjected to intensive GBNR in comparison with conventional Neurorehabilitation (NR) therapy using Berg balance scale (BBS), Parkinson disease questionnaire -39 scale (PDQ-39), Timed Up and Go test (TUG) and Box and block test (BBT).

Background: Physical exercise reinforces neuronal circuits that assist in stimulating gait (Herman et al., 2007). Researchers have also incorporated virtual reality into the NR process to assist in improvement of gait in individuals with PD (Liao et al., 2015). Here we have used MindMotion Go technology which is a type of GBNR. MindMotion GO consists of several cameras and a large screen. The patient is positioned in front of the device and plays video games using only their body movements, which are automatically captured and tracked by the cameras.

Method: A total 52 patients of PD were randomized using the block randomization method to 25 cases and 27 controls. Cases were subjected to 45 minutes of MindMotion-go neuro-rehabilitation with 45 minutes of gait and balance training, 5 times a week for 4 weeks and their pre, post NR and fourth week of follow up BBS, PDQ-39, TUG, BBT, UPDRS-3 and MMSE were taken while Controls were given conventional NR including strengthening exercises for the same time as cases (90 minutes) and the same scales were evaluated pre, post and at fourth week of conventional NR.

Results: We have analysed these data using Mann Whitney U test and Freidman test. In cases we found significant improvement in BBS, PDQ-39, TUG, BBT and UPDRS-3 post GBNR and significance persisted even at fourth week follow up. (P value of 0.0001). While in controls also we found significant improvement in BBS, PDQ-39, TUG, BBT and UPDRS-3, persisting at fourth week of follow up. (P-value of <0.05) Comparing the cases with controls showed statistically significant difference (P value <0.05) in TUG and BBS in GBNR group as compared to conventional NR group.

Conclusion: The present findings demonstrate that NR regardless of its type helps PD patients in improving their gait, balance and overall QOL but intensive GBNR along with gait and balance training exercises is slightly superior than conventional NR in Parkinson’s patients for functional improvement in the gait, balance, overall quality of life and reducing the risk of falls.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/effect-of-intensive-game-based-neurorehabilitation-gbnr-on-gait-balance-and-quality-of-life-qol-in-parkinsons-patients-a-prospective-randomized-control-study/