Objective: To determine the incidence of Parkinson’s disease (PD) and to find geographic variations in Mexico.

Background: PD is the third most prevalent neurological disease worldwide and incidence varies among studied populations. The reported annual incidence per 100,000 is of 17 globally,(1) 13.4 in the US,(2) 5 to 26 in Europe,(3) 8.7 in Asia.(4) Scarce epidemiological data exists in our country.

Method: Observational longitudinal study to report the annual incidence of PD patients in Mexico. Data was obtained from the National System of Epidemiological Vigilance, which documents data from public health institutions, including IMSS, ISSSTE, PEMEX, DIF, SEDEMA, and SEMAR. We report the mean incidence documented from 2014 to 2017.

Results: The reported incidence was of 6.7 in 2014, 9.5 in 2015, 10.3 in 2016, and 10.26 in 2017 per 100 000. The states with the highest reported incidence were Sinaloa with 27.43, Colima with 23.75, Durango with 19.73, Morelos with 18.54, and Chihuahua with 16.52 per 100 000. The states with the lowest reported incidence were Queretaro with 4.56, Zacatecas with 3.74, and Guanajuato with 3.22 per 100 000. The states with the highest incidence had a mean of 21.19 (16.52 – 27.43) compared to a mean of 8.92 (3.22 – 14.41) per 100 000 of the rest of the states in the country. The states with the highest incidence among patients younger than 50 years were Sinaloa with 9.92, Colima with 7.42, Jalisco with 6.7, Durango with 6.47 and Aguascalientes with 6.34 per 100 000.

Conclusion: The incidence of PD in Mexico is increasing annually and is lower compared to the reported global incidence. We observed a geographic variation with the highest incidence in the western states of Mexico. [figure1] Further studies that include populations from non-public institutions are required.

References: 1. Hirsch L, Jette N, Frolkis A, Steeves T, Pringsheim T. The Incidence of Parkinson’s Disease: A Systematic Review and Meta-Analysis. Neuroepidemiology. 2016;46(4):292-300. 2. Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, et al. Incidence of Parkinson’s disease: variation by age, gender, and race/ethnicity. Am J Epidemiol. 2003;157(11):1015-22. 3. von Campenhausen S, Bornschein B, Wick R, Botzel K, Sampaio C, Poewe W, et al. Prevalence and incidence of Parkinson’s disease in Europe. Eur Neuropsychopharmacol. 2005;15(4):473-90. 4. Muangpaisan W, Hori H, Brayne C. Systematic review of the prevalence and incidence of Parkinson’s disease in Asia. J Epidemiol. 2009;19(6):281-93.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/annual-incidence-of-parkinsons-disease-in-mexico-a-report-of-national-public-health-institutions/