Session Information
Date: Tuesday, June 21, 2016
Session Title: Tremor
Session Time: 12:30pm-2:00pm
Location: Exhibit Hall located in Hall B, Level 2
Objective: To evaluate clinical and neurophysiological features of ET and their phenotypes: classic (ET/Cl), ET with resting tremor (ET/RT), head (ET/H), voice (TE/V), chin (ET/Ch), lower limbs and trunk (ET/LL). To compared them with patients with Parkinson’s disease and ET (ET/PD).
Background: Essential tremor (ET) is a disorder characterized by the presence of bilateral and symmetrical action tremor involving the arms. It has several grades of amplitude and frequency. There are other atypical clinical phenotypes. Some patients with ET also develop Parkinsonian signs. Therefore there is debate about their possible etiologic relationship.
Methods: We included all the patients who concurred to perform a neurophysiologic assessment of tremor between January 2011 and May 2015 who met MDS consensus criteria for essential tremor. We considered sex, age, duration, characteristics of tremor, activation, amplitude, frequency and severity with Fahn-Tolosa-Marin scale. The diagnosis of PD was made according to UK PD Brain Bank Criteria.
Results: From 435 patients, 264 met ET criteria: 116 (44%) had the classic phenotype, 148 (56%) other atypical ET phenotypes; and 11 (4.1%) had ET/PD. Gender: Women 54.9%. The mean age was 68 years. There was a tendency of the average time of evolution (8.25 years) to be higher in atypical phenotypes and in TE/PD respect ET/CL. The clinical severity was mild for all variants. Atypical phenotypes had greater clinical impact, being statistical significant in TE/V phenotype.
Conclusions: ET/P D patients were older than the ET and their different phenotypes. Atypical ET phenotypes were more frequent in women and in who had a longer history of tremor. Classic ET patients had less clinical severity than the atypical features or when they associate PD. Voice tremor variant had, in average, greater functional impact than the other phenotypes.
52 Congreso Argentino de Neurologia.2015. Mar del Plata.Argentina. 68 Annual meeting AAN 2016.Vancouver.Canada.
To cite this abstract in AMA style:
J.S. Bestoso, L. Ciancaglini, C.V. Stefani, L.A. di Napoli, J.I. Rojas, D.J. Bauso, E. Cristiano. Essential tremor: Characterization according to their phenotypes and their association with Parkinsonian signs [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/essential-tremor-characterization-according-to-their-phenotypes-and-their-association-with-parkinsonian-signs/. Accessed September 7, 2024.« Back to 2016 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/essential-tremor-characterization-according-to-their-phenotypes-and-their-association-with-parkinsonian-signs/